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Weill Cornell Medicine scientists have built the first global database of clinical trials testing a rapidly expanding approach to cancer treatment that involves genetically modifying immune cells to recognize specific targets on a patient’s cancer cells and attack them. By analyzing the approach, called chimeric antigen receptor (CAR) therapies, the scientists designed a “therapeutic roadmap” that identifies all current therapies as well as additional cancers that can be treated with them....

Dr. Giuseppe Faraco publishes a paper titled, "Dietary salt promotes cognitive impairment through tau phosphorylation" in Nature, 2019 Oct 23. doi: 10.1038/s41586-019-1688-z.

“Our study proposes a new mechanism by which salt mediates cognitive impairment and also provides further evidence of a link between dietary habits and cognitive function,” This study finds that...

In the roughly 100 years since Alois Alzheimer first described the devastating neurodegenerative disease that now bears his name, scientists have developed an increasingly sophisticated understanding of the brain. Yet as incidence of the disease continues to rise in an aging population, effective treatments for Alzheimer’s disease remain elusive.

Leading experts in neurodegenerative disease gathered on Oct. 4 at the...

A novel mechanism that regulates activity in the brain, discovered by Weill Cornell Medicine investigators, may help explain the origins of one common type of dementia.

Frontotemporal dementia (FTD) primarily affects personality, emotion, behavior and motor function. It is the most common form of dementia in people under 60 years old. Investigators know that one form of FTD is caused by a mutant form of the tau protein in neurons in the brain, but exactly how this leads to dementia has...