Ketamine reverses neural changes underlying depression.

In a study published in Science 12 April 2019, Dr. Conor Liston and teams of scientists have identified that ketamine-induced changes in the brain are responsible for the remission of depression in mice. These findings may help researchers develop interventions that promote lasting remission of depression in humans.

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Study Shows How Ketamine Reverses Depression—and How its Benefits Could Be Extended

The powerful but temporary benefits of ketamine against depression might be extended if the new brain-cell connections it promotes could be preserved, according to a new study published April 12 in Science from researchers at Weill Cornell Medicine.

Depression affects tens of millions of people in the United States alone, which could lead to...

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Astronaut Twins Study Yields New Insights, Algorithms and Portable DNA Sequencing Tools

Long-term spaceflight causes more changes to gene expression than shorter trips, especially to the immune system and DNA repair systems, according to research by Weill Cornell Medicine and NASA investigators as part of NASA’s Twins Study, which followed the only set of identical twin astronauts for more than two years.  

Dr. Christopher Mason, an associate...

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Risk of Cardiovascular Event Jumps Significantly Before Cancer Diagnosis

Older adults with cancer are nearly 70 percent more likely to suffer a stroke or heart attack in the year prior to their diagnosis compared with peers without a cancer diagnosis in that same time period, according to new research by Weill Cornell Medicine, NewYork-Presbyterian and Memorial Sloan Kettering Cancer Center investigators.

The paper, published Dec. 21 in the...

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Measuring Brain Responses to Speech Provides Evidence of Cognition in Patients with Severe Brain Injury

Measuring brain activity in response to hearing a brief narrative can identify patients with severe brain injury who have preserved high-level cognition despite showing limited or no consciousness at the bedside, according to a study by Weill Cornell Medicine researchers.

The paper, published Nov. 21 in Current Biology, is the first to describe a method for measuring the delay in brain processing of...

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Study Clarifies ApoE4’s Role in Dementia

ApoE4, a protein linked to both Alzheimer’s disease and a form of dementia caused by damage of blood vessels in the brain, increases the risk of cognitive impairment by reducing the number and responsiveness of blood vessels in the organ, a study by Weill Cornell Medicine researchers suggests.

The study, published Sept. 19 in Nature...

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Early Sensory Stimulation is Critical for the Development of Sensory Networks

Sensory stimulation during a critical period soon after birth is essential for establishing networks in the brain that “map” sensations and enable the development of normal behaviors, according to a new study by Weill Cornell Medicine investigators.

The paper, published in print July 11 and online June 19 in Neuron, is the first to observe the early functional development of specialized nerve cells, called...

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Dr. Li Gan to Lead Appel Alzheimer’s Research Institute

Dr. Li Gan, a neuroscientist internationally acclaimed for her research into neurodegenerative diseases, has been appointed director of the Helen and Robert Appel Alzheimer’s Disease Research Institute at Weill Cornell Medicine.

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Leon Levy Fellowship Applications due July 1, 2018

Leon Levy Request for Applications  
Due: July 1st, 2018  

For application and questions - contact Veronica Bohorquez,

Costantino Iadecola, M.D.
Anne Parrish Titzell Professor of Neurology
Director and Chair, Feil Family Brain and Mind Research Institute

May 30...

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Winner of the 2017 BMRI Paper of the Year Award

Dear Colleagues:

  I am happy to report that the winner of the BMRI Paper of the Year Award is “Resting-state connectivity biomarkers define neurophysiological subtypes of depression.” Nat Med. (2017) 23(1):28-38, by Drysdale AT, Grosenick L, Downar J, Dunlop K, Mansouri F, Meng Y, Fetcho RN, Zebley B, Oathes DJ, Etkin A, Schatzberg AF, Sudheimer K, Keller J, Mayberg HS, Gunning FM, Alexopoulos GS, Fox MD, Pascual-Leone A, Voss HU, Casey BJ, Dubin MJ, Liston C.


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