CTNU Program Description
The Clinical and Translational Neuroscience Unit (CTNU) at the Brain and Mind Research Institute explores neurological disease through patient-oriented research programs. Directed by Dr. Hooman Kamel, CTNU allows fellows the opportunity to work with investigators from a variety of topics, from stroke to consciousness disorders. Find out more about our research below and check out our Fellowship Program.
Our research makes use of:
Administrative claims data from large populations- Example studies: Thrombosis in the postpartum state and Perioperative atrial fibrillation and stroke
- Example studies: Cancer and stroke in SEER-Medicare and Left atrial abnormality and stroke subtype in ARIC
- Example studies: Nonstenosing carotid plaque on MRA predicts ischemic stroke and Connectome disruption and post-stroke functional outcome
- Example studies: EEG and disorders of consciousness and Cerebral metabolic patterns in disorders of consciousness
- Example studies: Pathogenesis of weight loss in dementia and Hypothalamic dysfunction in Alzheimer’s Disease
Neurological Research Areas
Find the CTNU investigator who matches your field of neurological research.
- Hooman Kamel: atrial disease and stroke
- Babak Navi: cancer and stroke
- Ajay Gupta: atherosclerosis and stroke
- Ava Liberman: diagnostic strategies
- Alexander Merkler: myocardial disease and stroke
- Santosh Murthy: intracerebral hemorrhage
- Neal Parikh: liver disease and cognition
- Nicholas Schiff: disorders of consciousness
- Margaret Ross: neurogenetics
- Makoto Ishii: metabolic derangements in neurodegenerative disease
- Costantino Iadecola: vascular cognitive impairment, basic mechanisms of neurovascular function
Clinical Data Sources
Fellows have access to a rich variety of research data:
- CAESAR: a prospective registry spanning 2011-2018 and comprising approximately 3,000 cases of acute ischemic stroke and 600 cases of intracerebral hemorrhage.
- NUCLEUS: a registry of all patients in the Cornell Neuroscience Intensive Care Unit since 2012.
- Inpatient and outpatient claims data on a 5% nationally representative sample of Medicare beneficiaries from 2008-2018.
- Administrative claims data on all emergency department visits and acute care hospitalizations across 11 geographically dispersed states representing about 25% of the U.S. population.
- Nationwide Inpatient Sample from 1994-2019.
- Many other datasets such as NHANES, BRFSS, NSQIP, etc.
Research Funding
CTNU research programs are funded by NIH, organizations such as the American Academy of Neurology and the American Heart Association, and private philanthropic groups.
Research Opportunities
Learn more about the CTNU Fellowship Program.
Research Publications
The CTNU has published several papers in high-impact journals such as NEJM, JAMA, Circulation, and Annals of Neurology. These papers have all involved crucial participation from students, residents, and fellows, attesting to the positive educational impact of our group.
Browse our list of all CTNU publications.