CTNU Program Description
The Clinical and Translational Neuroscience Unit (CTNU) at the Brain and Mind Research Institute explores neurological disease through patient-oriented research programs. Directed by Dr. Hooman Kamel, CTNU allows fellows the opportunity to work with investigators from a variety of topics, from stroke to consciousness disorders. Find out more about our research below and check out our Fellowship Program.
Our research makes use of:Administrative claims data from large populations
- Example studies: Thrombosis in the postpartum state and Perioperative atrial fibrillation and stroke
- Example studies: Cancer and stroke in SEER-Medicare and Left atrial abnormality and stroke subtype in ARIC
- Example studies: Nonstenosing carotid plaque on MRA predicts ischemic stroke and Connectome disruption and post-stroke functional outcome
- Example studies: EEG and disorders of consciousness and Cerebral metabolic patterns in disorders of consciousness
Neurological Research Areas
Find the CTNU investigator who matches your field of neurological research.
- Hooman Kamel: atrial disease and stroke
- Babak Navi: cancer and stroke
- Ajay Gupta: atherosclerosis and stroke
- Alexander Merkler: myocardial disease and stroke
- Santosh Murthy: intracerebral hemorrhage
- Nicholas Schiff: disorders of consciousness
- Margaret Ross: neurogenetics
- Makoto Ishii: metabolic derangements in neurodegenerative disease
- Costantino Iadecola | Amy Kuceyeski | Ashish Raj: brain connectivity disorders
Clinical Data Sources
Fellows have access to a rich variety of research data:
- Cornell AcutE Stroke Academic Registry (CAESAR): a prospective registry spanning 2011-2017 and comprising 2,014 cases of acute ischemic stroke, 650 cases of intracerebral hemorrhage, and 550 cases of subarachnoid hemorrhage
- Inpatient and outpatient claims data on a 5% nationally representative sample of Medicare beneficiaries
- Administrative claims data on all emergency department visits and acute care hospitalizations in California, Florida, and New York from 2005-2016
- Nationwide Inpatient Sample from 1994-2016
CTNU research programs are funded by the NIH (grants U01NS095869, R01NS097443, K23NS082367, K23NS091395, and K08AG051179), organizations such as the American Academy of Neurology and the American Heart Association, and private philanthropic groups.
Learn more about the CTNU Fellowship Program.
The CTNU has published several papers in high-impact journals such as NEJM, JAMA, Circulation, and Annals of Neurology. These papers have all involved crucial participation from students, residents, and fellows, attesting to the positive educational impact of our group.