News

A three-year contract from Wellcome Leap will allow a team of investigators from Weill Cornell Medicine, Stanford Medicine and UC San Diego School of Medicine to study new ways to combat depression and create models that can predict which treatment is likely to work for individual patients.

“The purpose of this project is to develop new approaches to treating depression that work more effectively and in a more personalized way,” said principal investigator...

Hibiki Fujita  (PI)

Muscular Dystrophy Associations of America, Inc. MDA 961871-01
Genetic and metabolic strategies for mutant CHCHD10 neuromuscular disorders

Antoine Anfray  (PI)
BrightFocus Foundation A2022003F
Role of perivascular macrophages in ApoE4-induced neurovascular dysfunction

Keith P. Purpura  (PI)
National Eye Institute 1R01EY034150-01
Role of fixational eye...

Weill Cornell Medicine researchers are using machine learning, a form of artificial intelligence, to shed light on genetic mutations associated with spina bifida. In this birth defect, the neural tube that forms the spinal cord during pregnancy, does not close so that spinal nerves are exposed, resulting in paralysis and high risk of other complications.

Their new study, published online Dec. 16 in PNAS, “brings us closer to...

A gene mutation linked to Alzheimer’s disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new study by scientists at Weill Cornell Medicine. The team also found that blocking the pathway—with a drug that’s currently being tested in cancer clinical trials—protects against many features of the condition in a preclinical model. The results could lead to new strategies to...