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Center for Neurogenetics at Weill Cornell

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The Center for Neurogenetics was featured in the American Society of Human Genetics (ASHG) Annual Meeting October 6-10, 2020.

The Center for Neurogenetics (CNG) is a translational research hub that brings together clinicians, geneticists, neuroscientists, patients and family members to seek the underlying genetic contributions to and advanced therapeutics for disorders of the nervous system.

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New Developments in Dementia Research Presented at Appel Alzheimer's Disease Research Institute Symposium

Investigators on the forefront of research into neurodegenerative disorders shared some of their latest discoveries and possible implications for treatment at the eighth annual Appel Alzheimer's Disease Research Institute Symposium, held remotely on Oct. 14.

Sponsored by Weill Cornell Medicine’s Helen and Robert Appel Alzheimer’s Disease Research Institute and its home department, the...

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Alzheimer’s-Related Tau Protein Can Disrupt Blood Flow in the Brain, Long Before Neurodegeneration Sets In

Abnormal forms of a brain-cell protein called tau, which have long been implicated in Alzheimer’s and other neurodegenerative disorders, may contribute to neurodegeneration earlier than was previously understood, by interfering with the normal dynamics of blood flow in the brain, suggests a study from scientists at Weill Cornell Medicine. The results pave the way for research efforts that seek to prevent early neurodegeneration by restoring normal blood flow.

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Doctors Detail Unexpected Recoveries from Long-Term Coma After Cardiac Arrest

Neurologists traditionally have expected that patients who remain in coma after cardiac arrest have almost no chance of making a meaningful recovery if they fail to emerge from coma within a week. But a new study from Weill Cornell Medicine, NewYork-Presbyterian and NYU Grossman School of Medicine neurologists suggests that a small but significant fraction of such patients can recover even after much longer periods of coma...

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African American Patients Have Higher Risk of Stroke Recurrence Compared with White Patients

The short-term risk of a second stroke following an initial minor stroke is roughly 60 percent higher for black patients compared with white patients, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian researchers.

In the study, published Feb. 24 in JAMA Neurology, the researchers re-analyzed the results of a stroke prevention trial conducted at 269 sites worldwide, including...

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Sex Differences in Susceptibility to Neurodegenerative Disease May Arise From Differences in Brain Immune Cells

Immune cell activity in the brain differs between males and females in ways that may explain why some neurodegenerative diseases affect the sexes differently, according to a new study from Weill Cornell Medicine scientists.

The study, published Dec. 23 in Nature Neuroscience, compared brain-resident immune cells called microglia in male and female mice. Microglia in Alzheimer’s disease and other neurodegenerative disorders...

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Brain Immune Cells, Neurodegeneration Differ in Males, Females

Immune cell activity in the brain differs between males and females in ways that may explain why some neurodegenerative diseases affect the sexes differently, according to a new study from Weill Cornell Medicine scientists.

The study, published Dec. 23 in Nature Neuroscience, compared brain-resident immune cells called microglia in male and female mice. Microglia in Alzheimer’s disease and other neurodegenerative disorders...

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Scientists Build the First Global Database and Roadmap for CAR Therapy Clinical Trials

Weill Cornell Medicine scientists have built the first global database of clinical trials testing a rapidly expanding approach to cancer treatment that involves genetically modifying immune cells to recognize specific targets on a patient’s cancer cells and attack them. By analyzing the approach, called chimeric antigen receptor (CAR) therapies, the scientists designed a “therapeutic roadmap” that identifies all current therapies as well as additional cancers that can be treated with them....

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Dr. Costantino Iadecola Named Distinguished Scientist by the American Heart Association

Dr. Costantino Iadecola, director of the Feil Family Brain and Mind Research Institute and the Anne Parrish Titzell Professor of Neurology at Weill Cornell Medicine, has been recognized as a 2019 Distinguished Scientist by the American Heart Association for his outstanding contributions to cardiovascular, stroke and dementia research.

The American Heart Association (AHA) honored Dr....

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