News

Neuroscientist Dr. Gary Gibson keeps a framed picture of a cell derived from the skin cells of a person with Alzheimer’s disease on his office wall.

The image is a memento of Dr. Gibson’s breakthrough hypothesis about an underlying cause of mild cognitive impairment and Alzheimer’s – that an insufficiency of vitamin B1 called thiamine...

Inhibiting an immune signaling protein called TLR7 may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer’s disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine.

Most nerve fibers in vertebrates are encased in sheaths made largely of a protein called myelin, which protects the fibers and greatly enhances the efficiency of their signal...

A new study helps explain why having ApoE4—the gene variant most closely linked to Alzheimer’s disease—increases the risk of neurodegeneration and white matter damage. Researchers at Weill Cornell Medicine discovered that immune cells in the brain called border-associated macrophages (BAMs) are a source of ApoE4 protein and contribute to damaging blood vessels and brain tissue.

With surprising frequency, patients with severe brain injury can show clear signs of cognitive function on brain scans in response to requests to carry out complex mental work, even when they can’t move or speak, according to an international study co-led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

The study, published Aug. 14 in the New England Journal of Medicine, was the largest-ever...