News

Study Pinpoints Source of Free Radicals in the Brain that May Fuel Dementia

astrocytes

Researchers have discovered that free radicals generated at a specific site in non-neuronal brain cells called astrocytes, may promote dementia, according to a Weill Cornell Medicine study. Their findings, published Nov. 4 in Nature Metabolism, demonstrated that blocking this site lowered brain inflammation and protected neurons, suggesting a novel therapeutic...

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Grant Supports Studies to Improve and Personalize Bipolar Care

illustration of blue silhouette looking down and white silhouette looking straight ahead

A three-year, $4.5 million grant from BD²: Breakthrough Discoveries for thriving with Bipolar Disorder to Weill Cornell Medicine investigators, in collaboration with Stanford Medicine, will support a three-pronged research project to map the brain circuits that contribute to mood shifts in bipolar disorder and help develop personalized therapies for the condition.

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$1.1 Million Grant Funds Research on Rare Neurodevelopmental Disorder

Dr. Greenspan

A $1.1 million grant from the parent-caregiver-led Rare Bird Foundation to Weill Cornell Medicine is supporting the launch of a natural history study for a rare neurodevelopmental disorder that causes developmental delays and seizures called MEF2C Haploinsufficiency syndrome (MCHS).

Currently, there are no specific therapies for MCHS, which affects about 400 people worldwide. Patients with the condition may experience developmental delays,...

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Rewired

rewired
Neurologist Dr. Nicholas Schiff (M.D. ’92) has pioneered the use of deep brain stimulation in people with traumatic brain injury, helping them regain lost cognitive and motor skills. In parallel, he has worked to identify impaired patients with hidden cognitive function and is now seeking to test brain-computer interfaces that might help them.

Dr. Teresa Sanchez Awarded the Established Investigator Award from the American Heart Association

Teresa Sanchez

Dr. Teresa Sanchez, associate professor of pathology and laboratory medicine and associate professor of neuroscience in the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine, has been awarded the highly competitive Established Investigator Award from the American Heart Association.

The five-year, $550,000 grant supports mid-career...

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Looking Beyond Beta-Amyloid: New Paths in Alzheimer's Research

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At the 12th annual Helen and Robert Appel Alzheimer’s Disease Research Institute Symposium, scientists and clinicians shared their latest research which is advancing how Alzheimer’s disease is diagnosed and treated. Held at Weill Cornell Medicine’s Griffis Faculty Club, the...

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Mapping the Connections Between the Brain’s Structure and Function

brain connectomes

Using an algorithm they call the Krakencoder, researchers at Weill Cornell Medicine are a step closer to unraveling how the brain’s wiring supports the way we think and act. The study, published June 5 in Nature Methods, used imaging data from the Human Connectome Project...

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Brain Bleeds Increase the Risk of Dementia

dementia and hemorrhage

Weill Cornell Medicine researchers have found that intracranial hemorrhages, or "brain bleeds" caused by a ruptured blood vessel in the brain, double a person’s risk of developing dementia later in life.

While the connection between dementia and ischemic strokes caused by clots that block blood supply to the brain has received more attention, the...

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Decades of Work Leads to Clinical Trial for Early Alzheimer’s Treatment

Dr. Gary Gibson

Neuroscientist Dr. Gary Gibson keeps a framed picture of a cell derived from the skin cells of a person with Alzheimer’s disease on his office wall.

The image is a memento of Dr. Gibson’s breakthrough hypothesis about an underlying cause of mild cognitive impairment and Alzheimer’s – that an insufficiency of vitamin B1 called thiamine...

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Reducing Risk of Opioid Addiction While Alleviating Pain

reducing opiod addiction

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs’ ability to relieve pain, according to Weill Cornell Medicine investigators working with researchers from The Center for Youth Mental Health at NewYork-...

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