Feil Family Brain & Mind Research Institute

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A New Strategy for Protecting the Brain After Strokes

The chemical element selenium, an essential nutrient for humans and other animals, protects the brain after a stroke and may be a basis for future stroke therapies, according to a study from scientists at Burke Neurological Institute and Weill Cornell Medicine.

The study, published in print on May 16 and online May 2 in Cell, found that selenium drives a molecular response in brain cells that protects them from a...

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Exploring the disease-modifying effects of EH301 in mouse models of ALS

Giovanni Manfredi (PI)
ALS Association ALS 190452-01

Prefrontal circuit mechanisms underlying antidepressant effects of sleep deprivation: a role for metabotropic glutamate receptors

Puja Parekh (PI)
National Institute of Mental Health 1F32MH117973-01A1

Weill Cornell Medicine Experiences Dynamic Growth in Research Funding

Weill Cornell Medicine has experienced dynamic growth in its research enterprise over the past five years, an achievement that underscores the institution’s mission to provide patients with the most advanced treatments and therapies.

Since 2014, Weill Cornell Medicine’s research support from the National Institutes of Health has surged more than 40 percent. This expansion in the research enterprise coincides with the opening of the Belfer Research...

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Samantha Meadows Receives the 2019 National Science Foundation Graduate Research Fellowship

Astrocytes have many functions in the brain and have recently been shown to modulate cognition. However, it remains unclear exactly how astrocytes affect cognitive function and if those mechanisms are impaired by aging or disease.

The Orr laboratory is focused on understanding...

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Efficacy of biomarker-guided rTMS for treatment resistant depression

Conor Liston (PI)
National Institute of Mental Health 1R01MH118388-01

Ketamine reverses neural changes underlying depression.

In a study published in Science 12 April 2019, Dr. Conor Liston and teams of scientists have identified that ketamine-induced changes in the brain are responsible for the remission of depression in mice. These findings may help researchers develop interventions that promote lasting remission of depression in humans.

For more information:

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Study Shows How Ketamine Reverses Depression—and How its Benefits Could Be Extended

The powerful but temporary benefits of ketamine against depression might be extended if the new brain-cell connections it promotes could be preserved, according to a new study published April 12 in Science from researchers at Weill Cornell Medicine.

Depression affects tens of millions of people in the United States alone, which could lead to...

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Astronaut Twins Study Yields New Insights, Algorithms and Portable DNA Sequencing Tools

Long-term spaceflight causes more changes to gene expression than shorter trips, especially to the immune system and DNA repair systems, according to research by Weill Cornell Medicine and NASA investigators as part of NASA’s Twins Study, which followed the only set of identical twin astronauts for more than two years.  

Dr. Christopher Mason, an associate...

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Risk of Cardiovascular Event Jumps Significantly Before Cancer Diagnosis

Older adults with cancer are nearly 70 percent more likely to suffer a stroke or heart attack in the year prior to their diagnosis compared with peers without a cancer diagnosis in that same time period, according to new research by Weill Cornell Medicine, NewYork-Presbyterian and Memorial Sloan Kettering Cancer Center investigators.

The paper, published Dec. 21 in the...

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