In Brief: Smoking is Associated with Lower Cognitive Function in Older Adults

A person lighting a cigarette

Cigarette smoking is associated with worse cognitive performance among people 60 years and older, and that association is broadly the same whether or not individuals have hypertension or diabetes, according to a study from investigators at Weill Cornell Medicine and NewYork-Presbyterian. The findings, published Dec. 6 in the Journal of Alzheimer’s Disease, underscore smoking’s adverse effect on...

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Autism-linked Gene Shapes Nerve Connections

neurons stained red and green

A gene linked to autism spectrum disorders plays a critical role in early brain development and may shape the formation of both normal and atypical nerve connections in the brain, according to a new study by Weill Cornell Medicine investigators.

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New Theory Explains Recovery Delays in COVID-19 and Cardiac Patients

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COVID-19 patients placed on ventilators can take a long time to regain consciousness. New research from Weill Cornell Medicine, NewYork-Presbyterian, MIT, and Massachusetts General Hospital is now illustrating that these delays may serve a purpose: protecting the brain from oxygen deprivation.

The existence of such a brain-preserving state could explain why some patients wake up days or even weeks after they stop receiving ventilation, and it suggests that physicians should take these...

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New Developments in Dementia Research Presented at Appel Alzheimer's Disease Research Institute Symposium

A group of people together posing for a photo

The 10th annual Appel Alzheimer's Disease Research Institute Symposium brought fascinating reports of progress in understanding Alzheimer’s and related neurodegenerative diseases. The event was held at the Belfer Research Building on Oct. 25, before an in-person and Zoom audience.

Sponsored by Weill Cornell Medicine’s Helen and Robert Appel Alzheimer’s Disease Research Institute and its home department, the Feil Family Brain and Mind Research Institute, the event offered four...

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Academic Year 2022

Hibiki Fujita  (PI)

Muscular Dystrophy Associations of America, Inc. MDA 961871-01
Genetic and metabolic strategies for mutant CHCHD10 neuromuscular disorders

Antoine Anfray  (PI)
BrightFocus Foundation A2022003F
Role of perivascular macrophages in ApoE4-induced neurovascular dysfunction

Keith P. Purpura  (PI)
National Eye Institute 1R01EY034150-01
Role of fixational eye...

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Academic Year 2021

Gulcan Akgul (PI)

Brain & Behavior Research Foundation BBRF 29805-01
The Effects of Schizophrenia Associated Somatic Mutations on Connectivity and Function in Prefrontal Neocortical Circuits

Li Gan (PI)
National Institute on Aging 1 R01 AG074541-01
cGAS inhibitors for Alzheimer's disease treatment

Taylor Floyd (PI)
National Institute...

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Academic Year 2020

Drs. Anna and Adam Orr (PIs)

Daedalus Fund for Innovation of Weill Cornell Medicine BP 214689-01
Site-Specific Blockers of Mitochondrial FreeRadicals for Therapeutic Intervention in Neurodegenerative Diseases

Marilena D'Aurelio (PI)
National Institute of Neurological Disorders and Stroke 1R21NS118233-01A1
Modulation of intermediate metabolism, a new therapeutic approach for mitochondrial encephalomyopathies...

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Academic Year 2019

Jordi Magrane (PI)
Muscular Dystrophy Associations of America, Inc. MDAA 629299
Cell & non-cell autonomous effects of frataxin deficiency in FA pathophysiology

Subhash Sinha (PI)
The JPB Foundation JPG 205199-01
Developing compounds for Alzheimer disease target discovery and therapy

Song-Hai Shi (PI)
Simons Foundation Autism Research Initiative 567854...

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Academic Year 2018

Li Gan (PI)
Rainwater Charitable Foundation, RCF 190078-01
Tau Consortium

Conor Liston (PI)
NIMH 1R01MH118451-01
Regulation of prefrontal cortical circuit function and reward-seeking behavior by
stress-induced dendritic spine remodeling 

Giuseppe Faraco (PI)
Cure Alzheimer's Fund
Dietary salt, tau...

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Academic Year 2017

Jordi Magrane (PI)

The Friedreich’s Ataxia Research Alliance (FARA)
Functional analysis of primary sensory neurons and (proprio) sensory pathology
in Friedreich’s ataxia

Virginia Pickel (PI)
NIH grant R01DA042943
Aberrant prefrontal cortical plasticity and neurobehavioral consequences of adolescent marijuana

Thu Huynh (PI)

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