Key bacteria in onset and progression of MS identified

JCI cover May 2023

In a recent animal study, researchers from the Brain and Mind Research Institute at Weill Cornell Medicine have found that epsilon toxin — produced by a bacterium found in the small intestine — may trigger the onset of MS and cause continuing symptoms. The study is published in The Journal of Clinical Investigation, ...

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Gut microbiota, endothelial dysfunction and tau-mediated cognitive impairment

Guiseppe Faraco

Dr. Giuseppe Faraco received a grant from Cure Alzheimer’s Fund titled “Gut microbiota, endothelial dysfunction and tau-mediated cognitive impairment”. The grant aims at elucidating the link between microbiota-induced dysregulation of gut immunity, tau pathology & cognitive impairment.

Center for Neurogenetics at Weill Cornell

CNG Video image

The Center for Neurogenetics was featured in the American Society of Human Genetics (ASHG) Annual Meeting October 6-10, 2020.

The Center for Neurogenetics (CNG) is a translational research hub that brings together clinicians, geneticists, neuroscientists, patients and family members to seek the underlying genetic contributions to and advanced therapeutics for disorders of the nervous system.


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A high-salt diet may negatively affect cognitive function


Dr. Giuseppe Faraco publishes a paper titled, "Dietary salt promotes cognitive impairment through tau phosphorylation" in Nature, 2019 Oct 23. doi: 10.1038/s41586-019-1688-z.

“Our study proposes a new mechanism by which salt mediates cognitive impairment and also provides further evidence of a link between dietary habits and cognitive function,” This study finds that...

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Ketamine reverses neural changes underlying depression.

Dr. Conor Liston

In a study published in Science 12 April 2019, Dr. Conor Liston and teams of scientists have identified that ketamine-induced changes in the brain are responsible for the remission of depression in mice. These findings may help researchers develop interventions that promote lasting remission of depression in humans.

For more information:

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Dr. Li Gan to Lead Appel Alzheimer’s Research Institute

Dr. Li Gan

Dr. Li Gan, a neuroscientist internationally acclaimed for her research into neurodegenerative diseases, has been appointed director of the Helen and Robert Appel Alzheimer’s Disease Research Institute at Weill Cornell Medicine.

For more information:


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Leon Levy Fellowship Applications due July 1, 2018

Leon Levy Request for Applications  
Due: July 1st, 2018  

For application and questions - contact Veronica Bohorquez,

Costantino Iadecola, M.D.
Anne Parrish Titzell Professor of Neurology
Director and Chair, Feil Family Brain and Mind Research Institute

May 30...

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Winner of the 2017 BMRI Paper of the Year Award

Dear Colleagues:

  I am happy to report that the winner of the BMRI Paper of the Year Award is “Resting-state connectivity biomarkers define neurophysiological subtypes of depression.” Nat Med. (2017) 23(1):28-38, by Drysdale AT, Grosenick L, Downar J, Dunlop K, Mansouri F, Meng Y, Fetcho RN, Zebley B, Oathes DJ, Etkin A, Schatzberg AF, Sudheimer K, Keller J, Mayberg HS, Gunning FM, Alexopoulos GS, Fox MD, Pascual-Leone A, Voss HU, Casey BJ, Dubin MJ, Liston C.


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A High-Salt Diet Produces Dementia in Mice


A high-salt diet reduces resting blood flow to the brain and causes dementia in mice, according to a new study by scientists from Weill Cornell Medicine.

The study, published Jan. 15 in Nature Neuroscience, is the first to unveil a gut-brain connection linking high dietary salt intake to neurovascular and cognitive impairment. The findings illuminate a potential future target for countering harmful effects to the brain...

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The 2017 BMRI Paper of the Year Award

We are pleased to announce establishment of the inaugural “BMRI Paper of the Year Award”. A $10,000 unrestricted research grant will be given to the laboratory of the senior-corresponding author of a research paper published during the calendar year 2017, deemed by a peer-review panel to be the most impactful of those submitted for this competition. This award will be given annually, contingent upon availability of funds. ...

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