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Found 9 results
Author
Title
Type
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Year
]
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Keyword
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Amyloid beta-Peptides
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2014
Park L
,
Wang G
,
Moore J
,
Girouard H
,
Zhou P
,
Anrather J
,
Iadecola C
. 2014.
The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction.
.
Nat Commun. 5:5318.
Hu X
,
Li X
,
Zhao M
,
Gottesdiener A
,
Luo W
,
Paul S
. 2014.
Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.
.
Mol Neurodegener. 9:52.
Ishii M
,
Wang G
,
Racchumi G
,
Dyke JP
,
Iadecola C
. 2014.
Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.
.
J Neurosci. 34(27):9096-106.
2015
Ishii M
,
Iadecola C
. 2015.
Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology.
.
Cell Metab. 22(5):761-76.
2016
Koizumi K
,
Wang G
,
Park L
. 2016.
Endothelial Dysfunction and Amyloid-β-Induced Neurovascular Alterations.
.
Cell Mol Neurobiol. 36(2):155-65.
Zhao L
,
Gottesdiener AJ
,
Parmar M
,
Li M
,
Kaminsky SM
,
Chiuchiolo MJ
,
Sondhi D
,
Sullivan PM
,
Holtzman DM
,
Crystal RG
et al.
. 2016.
Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
.
Neurobiol Aging. 44:159-172.
Yuan P
,
Condello C
,
C Keene D
,
Wang Y
,
Bird TD
,
Paul SM
,
Luo W
,
Colonna M
,
Baddeley D
,
Grutzendler J
. 2016.
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
.
Neuron. 90(4):724-39.
2017
Kawamata H
,
Manfredi G
. 2017.
Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.
.
J Cell Biol. 216(12):3917-3929.
2022
Xia D
,
Lianoglou S
,
Sandmann T
,
Calvert M
,
Suh JH
,
Thomsen E
,
Dugas J
,
Pizzo ME
,
DeVos SL
,
Earr TK
et al.
. 2022.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
.
Mol Neurodegener. 17(1):41.