Apr 22 2021 - 4:00pm

Sidney Strickland, PhD, Zachary and Elizabeth M. Fisher Professor, The Rockefeller University
Abstract:
The fundamental pathology in Alzheimer’s disease (AD) is neuronal dysfunction leading to cognitive impairment. The amyloid-beta peptide (A), derived from amyloid precursor protein, is one driver of AD, but how it leads to neuronal dysfunction is not established. In this talk, I will discuss the complexity of AD and possible cause-and-effect relationships between A and the vascular and...
Apr 16 2021 - 12:00pm to 1:00pm

“Development of Small molecule inhibitors to modulate neuronal or microglial functions”
Subhash Sinha, PhD, Associate Professor of Research in Neuroscience, Appel Alzheimer’s Disease Research Institute, BMRI, WCM
Apr 15 2021 - 4:00pm to 5:00pm

Lu Chen, PhD, Professor
Stanford University, School of Medicine
Abstract:
Homeostatic plasticity and Hebbian plasticity are two major forms of activity-dependent plasticity that provide neural circuits the ability to modify its function in the face of an ever-changing environment. In this talk, I will discuss some of our recent efforts in investigating the functional interplays between Hebbian and homeostatic synaptic plasticity in vivo. I will focus in particular on how hippocampal...
Apr 9 2021 - 12:00pm to 1:00pm

“Psychiatric and cognitive sequelae of COVID-19: Perspectives from the first wave”
Abhishek Jaywant, PhD, Assistant Professor of Neuropsychology, Assistant Attending Psychologist, Departments of Psychiatry & Rehabilitation Medicine, WCM
Apr 2 2021 - 12:00pm to 1:00pm

“Disordered neurovascular coupling in a tauopathy mouse model: role of nNOS interneurons”
Sung Ji Ahn, PhD, Postdoctoral Associate in Neuroscience in the Iadecola lab, BMRI, WCM
Apr 1 2021 - 4:00pm to 5:00pm

Bennett Novitch, Ph.D.Professor and Ethel Scheibel Chair in NeuroscienceDepartment of NeurobiologyBroad Stem Cell Research CenterDavid Geffen School of Medicine at UCLA Abstract:
The remarkable information processing capacity of the human brain is thought to derive from its enormous mass, cellular density, and structural complexity. Defects in brain growth and organization result in a host of neurodevelopmental disorders, neuropsychiatric diseases, and intellectual disabilities. A key step...
Mar 26 2021 - 12:00pm to 1:00pm

“Lysosomal Exocytosis Releases Pathogenic -Synuclein Species from Neurons”
Ying Xue Xie, Graduate Student in the Sharma lab, Appel Alzheimer’s Disease Research Institute, BMRI, WCM
Mar 25 2021 - 4:00pm to 5:00pm

Oliver Rollins, PhD, Assistant Professor of Sociology, University of Louisville
While race, and especially its mistaken interpretation as a biological reality, has played a key role in the production of biological understandings of violence, recent research on violence using neuroimaging technologies reveals a conspicuous absence of race. Despite these efforts to move away from race, today’s neuroscience of violence is (still) haunted by what I call the “taboo of race.” In this talk, I...
Mar 19 2021 - 12:00pm to 1:00pm

"CAR T-cell Associated Neurotoxicity: Bedside to Bench and Back"
Bianca D. Santomasso, MD, PhD, Department of Neurology, Memorial Sloan Kettering Cancer Center
Mar 12 2021 - 12:00pm to 1:00pm

“Effects of Post-translational Modifications on Functional and Pathological Tau Interactions”
Diana Acosta, Neuroscience Graduate Student in the Eliezer lab, Departments of Biochemistry and BMRI, WCM