Nov 20 2020 - 12:00pm to 1:00pm
"Translating Neurotrophin Biology to Understand Risk for Psychiatric Disorders" Francis Lee, MD/PhD, Mortimer D. Sackler, M.D. Professor of Molecular Biology in Psychiatry, Chair of Psychiatry, Professor of Psychiatry, Neuroscience and Pharmacology, Depts. Of Psychiatry, Pharmacology and BMRI, WCM Please contact sot2002@med.cornell.edu for zoom details
Nov 19 2020 - 4:00pm to 5:00pm
Wade Harper Ph.D.,
Professor of Cell Biology, Harvard Medical School
The ubiquitin ligase Parkin, protein kinase PINK1, USP30 deubiquitylase, and p97 segregase function together to regulate turnover of damaged mitochondria via mitophagy, but our mechanistic understanding in neurons is limited. We have used induced neurons (iNeurons) derived from embryonic stem cells together with quantitative proteomics to reveal the dynamics and specificity of Parkin-dependent mitochondrial outer...
Nov 19 2020 - 4:00pm to 5:00pm
Wade Harper, Ph.D., Professor of Cell Biology, Harvard Medical School
Abstract: The ubiquitin ligase Parkin, protein kinase PINK1, USP30 deubiquitylase, and p97 segregase function together to regulate turnover of damaged mitochondria via mitophagy, but our mechanistic understanding in neurons is limited. We have used induced neurons (iNeurons) derived from embryonic stem cells together with quantitative proteomics to reveal the dynamics and specificity of Parkin-dependent mitochondrial...
Nov 13 2020 - 12:00pm to 1:00pm
"Multiple Sclerosis: What we don't know about myelin in this primary demyelinating disease. A clinical perspective"
Susan A. Gauthier, DO, MPH, Associate Professor of Clinical Neurology, Neurology in Radiology and Neuroscience, Depts. Of Neurology, Radiology & BMRI, WCM
Nov 6 2020 - 12:00pm to 1:00pm
“All of Us Research Hub”
Kelsey Mayo, PhD, Scientific Product & Portfolio Manager, Vanderbilt University Medical Center
Nov 5 2020 - 4:00pm to 5:00pm
"Deciphering the mechanisms controlling presynaptic Cav2 subtype levels and organization and their regulation of neurotransmitter release"
Samuel M. Young, Jr. PhD
Associate Professor
Department of Anatomy and Cell Biology, Director of Molecular Auditory Research, Department of Otolaryngology
University of Iowa
The diversity of information encoding by neuronal circuits is regulated by the magnitude and location of Ca2+ entry though voltage-gated Ca2+ channels (CaV). In the mammalian...
Nov 5 2020 - 4:00pm to 6:00pm
Target Audience – Patients who would benefit from understanding how best to navigate the complex health system and be made aware of the supportive services available to help them coordinate care. Providers to understand the challenges that patients face. From disciplines of rare disease such as melanoma, brain cancers, and sarcoma among others.
Goals – In alignment with the Dan McMenamin Endowment (DME) mission, the event strives to foster cooperation among patients, physicians, and...
Oct 30 2020 - 12:00pm to 1:00pm
“New Therapeutic Avenues for the Treatment of Age-Related Neurodegenerative Diseases”
Victor Tapias Molina, PhD, Assistant Professor of Research in Neuroscience, BMRI, WCM
Oct 23 2020 - 12:00pm to 1:00pm
“Neurological Complications of Covid-19”
Alexander E. Merkler, MD, Assistant Professor of Neurology and Neuroscience, Division of Neurocritical Care & BMRI, Site Director, NY-Presbyterian Neurocritical Care Fellowship, WCM
Oct 22 2020 - 4:00pm
Fenghua Hu, Ph.D., Associate Professor, Cornell University
Frontotemporal dementia (FTD) is a devastating neurodegenerative disease characterized by the degeneration of neurons in the frontal and temporal lobes. Haploinsufficiency of the progranulin (PGRN) protein is one of leading causes of FTD. PGRN is a secreted glycoprotein comprised of 7.5 granulin repeats. Interestingly, we found that PGRN is a lysosome resident protein and accumulating evidence support that PGRN is essential for...