Oct 28 2021 - 4:00pm to 5:00pm

Part of the Progress in Neuroscience Seminar (PINS) series
Timothy H. Murphy Ph.D.
Professor
University of British Columbia
Abstract
The central focus of my lab is in understanding how cortical activity flow impacts normal brain function and diseases of the nervous system such as stroke. My laboratory contributes to understanding how a mouse cortex adapts after stroke, resulting in remapping of brain function from damaged to surviving areas using mouse models. The lab has developed new...
Oct 22 2021 - 12:00pm to 1:00pm

Kimberly Marks, BS, PhD Candidate in Neuroscience (Anrather lab), BMRI, WCM
Oct 21 2021 - 4:00pm to 5:00pm

Part of the Progress in Neuroscience Seminar (PINS) series
Serge Charpak, M.D., Ph.D.
Inserm Research Director
Abstract
"I will describe a decade of research on how functional imaging based on blood flow dynamics actually reports neuronal activation. Our approach is based on two-photon microscopy imaging of cellular activity, functional ultrasound imaging of blood volume (fUS) and BOLD fMRI in the rodent brain."
Publications
Aydin AK, Haselden WD, Goulam Houssen Y, Pouzat C, Rungta RL,...
Oct 15 2021 - 12:00pm to 1:00pm

Hagen Tilgner, PhD, Assistant Professor of Neuroscience, Center for Neurogenetics, BMRI, WCM
Oct 14 2021 - 4:00pm to 5:00pm

Patrick J. Drew, PhD
Huck Distinguished Associate Professor of Neural Engineering and Neurosurgery, Depts. of Engineering Science and Mechanics, Neurosurgery, and Biomedical Engineering, The Pennsylvania State University
Abstract:
In the brain, increases in blood flow and oxygenation are correlated to increases in neural activity. While this correlation is extensively used in human brain imaging, the mechanisms underlying the linkage between neural activity and hemodynamics are poorly...
Oct 8 2021 - 12:00pm to 1:00pm

Brain and Mind Research Institute (BMRI): Work in Progress (WIP)
Andrei I. Holodny, M.D., Ph.D., FACR
Memorial Sloan-Kettering Cancer Center Neuroradiology Service Chief and Functional MRI Laboratory Director
Weill Cornell Medicine Radiology and Graduate School Neuroscience Professor
Oct 7 2021 - 4:00pm to 5:00pm

Jimcy Platholi, PhD, Assistant Professor of Neuroscience in Anesthesiology, WCM
Publications:
Johnson, Herold, Milner, Hemmings, and Platholi. Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus. J. Comp Neurol 2017 525: 3563-3578.
Platholi, Herold, Hemmings, Halpain. Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism. PLos One 2014 9:e102978.
Sep 30 2021 - 4:00pm to 5:00pm

“Lipids and the demise of neurons; from rare to common diseases”
Hugo J Bellen, DVM, PhD
Departments of Molecular and Human Genetics and Neuroscience, Baylor College of Medicine
Sep 30 2021 - 4:00pm to 5:00pm

Hugo J Bellen, DVM, PhD, Departments of Molecular and Human Genetics and Neuroscience, Baylor College of Medicine
Abstract:
I will present data that show that rare neurological diseases can serve as model for much more common diseases such as AD, PD and MS. Importantly, these disease affect lipid metabolism and I will argue that different lipids are at the root of these neurodegenerative diseases.
Publications:
Moulton MJ, Barish S, Ralhan I, Chang J, Goodman LD, Harland J,...
Sep 23 2021 - 4:00pm to 5:00pm

Jesse Goldberg, MD,PhD, Associate Professor of Neurobiology and Behavior
Abstract:
Attending to mistakes while practicing alone provides opportunities for learning, but self-evaluation during audience-directed performance could distract from ongoing execution. It remains unknown how animals switch between practice and performance modes, and how evaluation systems process errors across distinct performance contexts. We recorded from striatal-projecting dopamine (DA) neurons as male songbirds...