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A
Carling GK
,
Fan L
,
Foxe NR
,
Norman K
,
Ye P
,
Wong MYing
,
Zhu D
,
Yu F
,
Xu J
,
Yarahmady A
et al.
. 2024.
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
.
bioRxiv.
Shi Y
,
Yamada K
,
Liddelow SAntony
,
Smith ST
,
Zhao L
,
Luo W
,
Tsai RM
,
Spina S
,
Grinberg LT
,
Rojas JC
et al.
. 2017.
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
.
Nature. 549(7673):523-527.
Cao J
,
Gaamouch FEl
,
Meabon JS
,
Meeker KD
,
Zhu L
,
Zhong MB
,
Bendik J
,
Elder G
,
Jing P
,
Xia J
et al.
. 2017.
ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.
.
Sci Rep. 7(1):11372.
C
Dorkenwald S
,
Schneider-Mizell CM
,
Brittain D
,
Halageri A
,
Jordan C
,
Kemnitz N
,
Castro MA
,
Silversmith W
,
Maitin-Shephard J
,
Troidl J
et al.
. 2023.
CAVE: Connectome Annotation Versioning Engine.
.
bioRxiv.
Ding W
,
Stohl LL
,
Xu L
,
Zhou XK
,
Manni M
,
Wagner JA
,
Granstein RD
. 2023.
Correction: Calcitonin Gene-Related Peptide-Exposed Endothelial Cells Bias Antigen Presentation to CD4+ T Cells toward a Th17 Response.
.
J Immunol.
Deglincerti A
,
Liu Y
,
Colak D
,
Hengst U
,
Xu G
,
Jaffrey SR
. 2015.
Coupled local translation and degradation regulate growth cone collapse.
.
Nat Commun. 6:6888.
D
Telpoukhovskaia MA
,
Liu K
,
Sayed FA
,
Etchegaray JIker
,
Xie M
,
Zhan L
,
Li Y
,
Zhou Y
,
Le D
,
Bahr BA
et al.
. 2020.
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.
.
Sci Rep. 10(1):13688.
Guiberson NGuy Lewis
,
Black LS
,
Haller JE
,
Brukner A
,
Abramov D
,
Ahmad S
,
Xie YXin
,
Sharma M
,
Burré J
. 2024.
Disease-linked mutations in Munc18-1 deplete synaptic Doc2.
.
Brain.
E
Ma Y
,
Sannino D
,
Linden JR
,
Haigh S
,
Zhao B
,
Grigg JB
,
Zumbo P
,
Dündar F
,
Butler DJ
,
Profaci CP
et al.
. 2023.
Epsilon toxin-producing Clostridium perfringens colonize the MS gut and epsilon toxin overcomes immune privilege.
.
J Clin Invest.
Zook JM
,
Catoe D
,
McDaniel J
,
Vang L
,
Spies N
,
Sidow A
,
Weng Z
,
Liu Y
,
Mason CE
,
Alexander N
et al.
. 2016.
Extensive sequencing of seven human genomes to characterize benchmark reference materials.
.
Sci Data. 3:160025.
Zook JM
,
Catoe D
,
McDaniel J
,
Vang L
,
Spies N
,
Sidow A
,
Weng Z
,
Liu Y
,
Mason CE
,
Alexander N
et al.
. 2016.
Extensive sequencing of seven human genomes to characterize benchmark reference materials.
.
Sci Data. 3:160025.
F
Garg A
,
Hannan A
,
Wang Q
,
Collins T
,
Teng S
,
Bansal M
,
Zhong J
,
Xu K
,
Zhang X
. 2018.
FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination.
.
PLoS Genet. 14(9):e1007660.
G
Sziraki A
,
Lu Z
,
Lee J
,
Banyai G
,
Anderson S
,
Abdulraouf A
,
Metzner E
,
Liao A
,
Banfelder J
,
Epstein A
et al.
. 2023.
A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains.
.
Nat Genet.
Xu P
,
Chang JC
,
Zhou X
,
Wang W
,
Bamkole M
,
Wong E
,
Bettayeb K
,
Jiang L-L
,
Huang T
,
Luo W
et al.
. 2021.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
.
J Exp Med. 218(8)
Xu P
,
Chang JC
,
Zhou X
,
Wang W
,
Bamkole M
,
Wong E
,
Bettayeb K
,
Jiang L-L
,
Huang T
,
Luo W
et al.
. 2021.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
.
J Exp Med. 218(8)
Hawrylycz M
,
Martone ME
,
Ascoli GA
,
Bjaalie JG
,
Dong H-W
,
Ghosh SS
,
Gillis J
,
Hertzano R
,
Haynor DR
,
Hof PR
et al.
. 2023.
A guide to the BRAIN Initiative Cell Census Network data ecosystem.
.
PLoS Biol. 21(6):e3002133.
Hawrylycz M
,
Martone ME
,
Ascoli GA
,
Bjaalie JG
,
Dong H-W
,
Ghosh SS
,
Gillis J
,
Hertzano R
,
Haynor DR
,
Hof PR
et al.
. 2023.
A guide to the BRAIN Initiative Cell Census Network data ecosystem.
.
PLoS Biol. 21(6):e3002133.
I
Gilani AI
,
Chohan MO
,
Inan M
,
Schobel SA
,
Chaudhury NH
,
Paskewitz S
,
Chuhma N
,
Glickstein S
,
Merker RJ
,
Xu Q
et al.
. 2014.
Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition.
.
Proc Natl Acad Sci U S A. 111(20):7450-5.
L
Xie YXue
,
Naseri NN
,
Fels J
,
Kharel P
,
Na Y
,
Lane D
,
Burré J
,
Sharma M
. 2022.
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
.
Nat Commun. 13(1):4918.
M
Zheng X
,
Wu B
,
Liu Y
,
Simmons SK
,
Kim K
,
Clarke GS
,
Ashiq A
,
Park J
,
Li J
,
Wang Z
et al.
. 2024.
Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development.
.
Cell.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
N
Celii B
,
Papadopoulos S
,
Ding Z
,
Fahey PG
,
Wang E
,
Papadopoulos C
,
Kunin AB
,
Patel S
,
J Bae A
,
Bodor AL
et al.
. 2023.
NEURD: automated proofreading and feature extraction for connectomics.
.
bioRxiv.
Kong W
,
Frouard J
,
Xie G
,
Corley MJ
,
Helmy E
,
Zhang G
,
Schwarzer R
,
Montano M
,
Sohn P
,
Roan NR
et al.
. 2024.
Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.
.
PNAS Nexus. 3(5):pgae179.
Xia D
,
Lianoglou S
,
Sandmann T
,
Calvert M
,
Suh JH
,
Thomsen E
,
Dugas J
,
Pizzo ME
,
DeVos SL
,
Earr TK
et al.
. 2022.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
.
Mol Neurodegener. 17(1):41.
P
Sohn PDongmin
,
Huang CTzu-Ling
,
Yan R
,
Fan L
,
Tracy TE
,
Camargo CM
,
Montgomery KM
,
Arhar T
,
Mok S-A
,
Freilich R
et al.
. 2019.
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
.
Neuron. 104(3):458-470.e5.
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