Feil Family Brain & Mind Research Institute

Publications

Found 14 results
Author Title Type [ Year(Asc)]
Filters: Keyword is Mitochondria  [Clear All Filters]
2025
Larrea D, Tamucci KA, Kabra K, Velasco KR, Yun TD, Pera M, Montesinos J, Agrawal RR, Paradas C, Smerdon JW et al..  2025.  Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS).. Nat Commun. 16(1):379.
Liao S-C, Kano K, Phanse S, Nguyen M, Margolis E, Fu YH, Meng JX, Moutaoufik MTaha, Chatterton Z, Saccon T et al..  2025.  CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.. Sci Adv. 11(46):eadu0726.
Woo E, Tasnim F, Kawamata H, Manfredi G, Konrad C.  2025.  Investigation of mitochondrial phenotypes in motor neurons derived by direct conversion of fibroblasts from familial ALS subjects.. Cell Death Dis. 17(1):51.
Barnett D, Zimmer TS, Booraem C, Palaguachi F, Meadows SM, Xiao H, Wong MYing, Luo W, Gan L, Chouchani ET et al..  2025.  Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.. Nat Metab. 7(11):2300-2323.
Siragusa M, Yoval-Sánchez B, Guerrero I, Galkin A.  2025.  Postnatal developmental dynamics of mitochondrial complex I in mouse tissues.. Am J Physiol Cell Physiol. 329(5):C1666-C1671.
2024
Bennett NK, Lee M, Orr AL, Nakamura K.  2024.  Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production.. Proc Natl Acad Sci U S A. 121(3):e2307904121.
2017
Starkov AA, Chinopoulos C, Starkova NN, Konrad C, Kiss G, Stepanova A, Popov VN.  2017.  Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria.. J Bioenerg Biomembr. 49(1):3-11.
Kawamata H, Manfredi G.  2017.  Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.. J Cell Biol. 216(12):3917-3929.
Tapias V, Hu X, Luk KC, Sanders LH, Lee VM, J Greenamyre T.  2017.  Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production.. Cell Mol Life Sci. 74(15):2851-2874.
2016
Stepanova A, Shurubor Y, Valsecchi F, Manfredi G, Galkin A.  2016.  Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart.. Biochim Biophys Acta. 1857(9):1561-8.
Chandra A, Sharma A, Calingasan NY, White JM, Shurubor Y, X Yang W, M Beal F, Johri A.  2016.  Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease.. Hum Mol Genet. 25(11):2269-2282.
Manfredi G, Kawamata H.  2016.  Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.. Neurobiol Dis. 90:35-42.
Chung SYoung, Kishinevsky S, Mazzulli JR, Graziotto J, Mrejeru A, Mosharov EV, Puspita L, Valiulahi P, Sulzer D, Milner TA et al..  2016.  Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation.. Stem Cell Reports. 7(4):664-677.
Esmaeili MA, Yadav S, Gupta RKr, Waggoner GR, DeLoach A, Calingasan NY, M Beal F, Kiaei M.  2016.  Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.. Hum Mol Genet. 25(2):317-27.