Title | A Novel Neurovascular Liaison Governing the Blood-Brain Barrier. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Ishii M, Iadecola C |
Journal | Neuron |
Volume | 107 |
Issue | 2 |
Pagination | 205-207 |
Date Published | 2020 Jul 22 |
ISSN | 1097-4199 |
Abstract | How circulating signals enter the median eminence to trigger homeostatic hypothalamic responses is not well understood. Jiang et al. describe a neural mechanism that increases endothelial fenestrations and enhances the hypothalamic response to the circulating hormone leptin, suggesting a novel way to regulate brain entry through vascular wall remodeling. |
DOI | 10.1016/j.neuron.2020.06.024 |
Alternate Journal | Neuron |
PubMed ID | 32702343 |