Hooman Kamel, M.D.
Assistant Professor of Neurology
Assistant Professor of Neuroscience, BMRI
Biography
Hooman Kamel, MD attended college at Harvard and medical school at Columbia, and trained as a neurology resident and neurocritical care fellow at the University of California, San Francisco. He now serves as an assistant professor in the Department of Neurology and the Brain and Mind Research Institute at New York-Presbyterian Hospital/Weill Cornell Medical College. His clinical duties involve caring for critically ill patients with neurological diseases such as stroke, brain hemorrhage, and traumatic brain injury. He spends the majority of his time as a clinical scientist focused on discovering new ways to prevent strokes caused by heart disease. His research has been published in top medical journals such as the New England Journal of Medicine and JAMA, and he serves on the editorial boards of Journal Watch Neurology, PLOS One, and Scientific Reports. He is a past recipient of a Scientist Development Grant from the American Heart Association, and his research is currently funded by the National Institutes of Health. His academic contributions to the field of stroke have been recognized by honors such as the Michael S. Pessin Stroke Leadership Prize from the American Academy of Neurology.
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My Mission
I am a neurologist and clinical scientist whose research focuses on stroke prevention. I am currently investigating novel associations between cardiac arrhythmias and ischemic stroke. Discovering new links between heart disease and stroke may have important near-term implications for improving stroke prevention, because several approved drugs have proven efficacy in treating currently recognized sources of cardiac embolism.
My work spans the clinical and translational neuroscience spectrum. Our research program relies on a combination of state-level administrative claims data to study disease at a population level, detailed clinical and physiological data from large-scale epidemiological studies, and exploratory biomarker studies in carefully selected cohorts of patients with stroke. This research program was previously funded by a Scientist Development Grant from the American Heart Association, and is currently funded by a K23 award from the National Institute of Neurological Disorders and Stroke.
Goals
To identify novel associations between electrocardiographic markers of cardiac disease and the risk of stroke, to ultimately reduce the burden of stroke by identifying strong risk factors.
Achievements
- Identified a novel association between paroxysmal supraventricular tachycardia (PSVT) and ischemic stroke.
- Identified a novel association between major perioperative hemorrhage and the risk of stroke and myocardial infarction.
- Demonstrated that the risk of thrombotic events remains elevated beyond the traditional 6-week postpartum period, and persists for at least 12 weeks after labor and delivery.
Publications
- Kamel H, Johnson SC, Easton JD, Kim AS. Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in patients with atrial fibrillation and prior stroke or transient ischemic attack. Stroke. 2012;43:881-883.
- Kamel H, Johnston SC, Kirkham JC, Turner CG, Kizer JR, Devereux RB, Iadecola C. Association between major perioperative hemorrhage and stroke or Q-wave myocardial infarction. Circulation. 2012;126:207-212.
- Kamel H, Easton JD, Johnson SC, Kim AS. Cost-effectiveness of apixaban vs warfarin for secondary stroke prevention in atrial fibrillation. Neurology. 2012;79:1428-1434.
- Kamel H, Navi BB, Elijovich L, Josephson SA, Yee AH, Fung G, Johnston SC, Smith WS. Pilot randomized trial of outpatient cardiac monitoring after cryptogenic stroke. Stroke. 2013;44:528-530.
- Kamel H, Elkind MSV, Bhave PD, Navi BB, Okin PM, Iadecola C, Devereux RB, Fink ME. Paroxysmal supraventricular tachycardia and the risk of ischemic stroke. Stroke. 2013;44:1550-1554.
- Kamel H, Navi BB, Fahimi J. National trends in ambulance use by patients with stroke, 1997-2008. JAMA. 2012;307:1026-1028.
- Fahimi J, Navi BB, Kamel H. Potential misdiagnosis of Bell’s palsy in the emergency department. Ann Emerg Med. Epub 2013 Jul 18.
- Mangla A, Navi BB, Layton K, Kamel H. Transient global amnesia and the risk of ischemic stroke. Stroke. 2014;45:389-393.
- Kamel H, Navi BB, Sriram N, Hovsepian DA, Devereux RB, Elkind MSV. Risk of a thrombotic event after the 6-week postpartum period. N Eng J Med. Epub 2014 Feb 13.
Joint Appointments
My primary appointment is in the Department of Neurology, and my secondary appointment is in the BMRI.
Collaborations
Costantino Iadecola, Richard Devereux, Peter Okin, Babak Navi, Matthew Fink, Ajay Gupta, Ankur Pandya, Amy Kuceyeski, Ashish Raj.