Feil Family Brain & Mind Research Institute

Publications

Found 85 results

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2026

Honey MIJ, Hok-A-Hin YS, Thijssen EH, Cousins KAQ, van der Weijden B, Veld LIn 't, Stoops E, de Boer SCM, Duits FH, de Houwer JFH et al.. 2026. An acetylated Tau-174 CSF biomarker discriminates between TDP-43 and tau pathology in patients with frontotemporal lobar degeneration.. Nat Med.

Jati S, Taheri S, Kal S, Sinha SC, Head BP, Mahata SK, Sahoo D. 2026. AI guided discovery of a murine model of asymptomatic Alzheimer's disease.. Acta Neuropathol Commun.

2025

Larrea D, Tamucci KA, Kabra K, Velasco KR, Yun TD, Pera M, Montesinos J, Agrawal RR, Paradas C, Smerdon JW et al.. 2025. Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS).. Nat Commun. 16(1):379.

Barbier M, Rajamani KThirtamara, Netser S, Wagner S, Harony-Nicolas H. 2025. Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3-Deficient Rats.. Adv Sci (Weinh). :e2414813.

Martinez-Meza S, Premeaux TA, Cirigliano SM, Friday CM, Michael S, Mediouni S, Valente ST, Ndhlovu LC, Fine HA, O'Brien RLFurler et al.. 2025. Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model.. J Neuroinflammation. 22(1):66.

Brezzo G, Zera KA, Straus DE, Goertz JE, Loppi SH, Crumpacker RR, Frye JB, Becktel DA, Cuartero MIsabel, Culebras AGarcía et al.. 2025. Assessing post-stroke cognition in pre-clinical models: Lessons and recommendations from a multi-center study.. J Cereb Blood Flow Metab. :271678X251400241.

Andres W, Bruce S, Merkler AEliot, Iadecola C, de Leon MJ, Chiang GC, Kamel H, Zhang C, Murthy SB. 2025. Association Between Cerebral Amyloid Angiopathy and Nontraumatic Subdural Hemorrhage.. Neurology. 104(10):e213614.

Zheng H, Feng Y, Tang J, Yu F, Wang Z, Xu J, Hai C, Jiang M, Cheng Y, Shao Z et al.. 2025. Astrocyte-secreted cues promote neural maturation and augment activity in human forebrain organoids.. Nat Commun. 16(1):2845.

Li D, Li J, Johann DJ, Butler D, Chen G, Foox J, Gong B, Jones W, Kreil DP, Kusko R et al.. 2025. Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations.. NPJ Precis Oncol. 9(1):182.

2024

Kloske CM, Belloy ME, Blue EE, Bowman GR, Carrillo MC, Chen X, Chiba-Falek O, Davis AA, Di Paolo G, Garretti F et al.. 2024. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.. Alzheimers Dement.

Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al.. 2024. Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.

Carling GK, Fan L, Foxe NR, Norman K, Wong MYing, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A et al.. 2024. Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. Neuron.

Garcia-Bonilla L, Shahanoor Z, Sciortino R, Nazarzoda O, Racchumi G, Iadecola C, Anrather J. 2024. Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke.. Nat Immunol. 25(2):357-370.

Bravo CParra, Krukowski K, Barker S, Wang C, Li Y, Fan L, Vázquez-Rosa E, Shin M-K, Wong MYing, McCullough LD et al.. 2024. Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.. Mol Neurodegener. 19(1):51.

Sanz LRD, Lejeune N, Szymkowicz E, Bonin EAC, Panda R, Sala A, Thibaut A, Huerta-Gutierrez R, Dardenne N, Dikenstein D et al.. 2024. Apomorphine for prolonged disorders of consciousness: a multimodal open-label study.. EClinicalMedicine. 78:102925.

Cheng F, Wang F, Tang J, Zhou Y, Fu Z, Zhang P, Haines JL, Leverenz JB, Gan L, Hu J et al.. 2024. Artificial intelligence and open science in discovery of disease-modifying medicines for Alzheimer's disease.. Cell Rep Med. 5(2):101379.

Parikh NS, Zhang C, Bruce SS, Murthy SB, Rosenblatt R, Liberman AL, Liao V, Kaiser JH, Navi BB, Iadecola C et al.. 2024. Association between elevated fibrosis-4 index of liver fibrosis and risk of hemorrhagic stroke.. Eur Stroke J. :23969873241259561.

Harris W, Kaiser JH, Liao V, Avadhani R, Iadecola C, Falcone GJ, Sheth KN, Qureshi AI, Goldstein JN, Awad IA et al.. 2024. Association Between Hematoma Volume and Risk of Subsequent Ischemic Stroke: A MISTIE III and ATACH-2 Analysis.. Stroke. 55(3):541-547.

Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S-Y, Li X, Christensen T, Salisbury JL, Geroux RE, Gateno B et al.. 2024. Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice.. Commun Biol. 7(1):234.

2023

Prjibelski AD, Mikheenko A, Joglekar A, Smetanin A, Jarroux J, Lapidus AL, Tilgner HU. 2023. Accurate isoform discovery with IsoQuant using long reads.. Nat Biotechnol.

Boato F, Guan X, Zhu Y, Ryu Y, Voutounou M, Rynne C, Freschlin CR, Zumbo P, Betel D, Matho K et al.. 2023. Activation of MAP2K signaling by genetic engineering or HF-rTMS promotes corticospinal axon sprouting and functional regeneration.. Sci Transl Med. 15(677):eabq6885.

Luo W, Qu W, Gan L. 2023. The AD odyssey 2023: Tales of single cell.. Cell. 186(20):4257-4259.

Barbier M, Rajamani KThirtamara, Netser S, Wagner S, Harony-Nicolas H. 2023. Altered neural activity in the mesoaccumbens pathway underlies impaired social reward processing in Shank3-deficient rats.. bioRxiv.

Das M, Mao W, Voskobiynyk Y, Necula D, Lew I, Petersen C, Zahn A, Yu G-Q, Yu X, Smith N et al.. 2023. Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.. Neurobiol Dis. 186:106263.

Lee H, Lee K, Kim YDae, Nam HSuk, Lee HSun, Cho S, Heo JHoe. 2023. Association between substantia nigra degeneration and functional outcome in patients with basal ganglia infarction.. Eur J Neurol.