Feil Family Brain & Mind Research Institute

Publications

Found 45 results
Author Title Type [ Year(Asc)]
Filters: Keyword is Disease Models, Animal  [Clear All Filters]
2026
Chi Y, DiKun KM, Tang X-H, Warren CD, Chikara S, Del Aguila EMere, Wagner JA, Geri JB, Gudas LJ.  2026.  Retinoic acid receptor β deletion in podocytes causes kidney and liver dysfunction, modeling nephrotic syndrome.. J Mol Endocrinol. 76(1)
2025
Birnbaum EM, Xie L, Serrano P, Rockwell P, Figueiredo-Pereira ME.  2025.  BT-11 targets the LANCL2 pathway to attenuate cognitive deficits and hippocampal pathology in Alzheimer's transgenic rats.. Sci Rep. 16(1):1848.
Khawaja RR, Griego E, Lindenau K, Salek A, Gambardella J, Scrivo A, Monday HR, Bourdenx M, Madero-Pérez J, Khan ZN et al..  2025.  Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome.. Nat Cell Biol. 27(10):1688-1707.
Liao S-C, Kano K, Phanse S, Nguyen M, Margolis E, Fu YH, Meng JX, Moutaoufik MTaha, Chatterton Z, Saccon T et al..  2025.  CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.. Sci Adv. 11(46):eadu0726.
Chen H, Fan L, Guo Q, Wong MYing, Zhu J, Foxe N, Wang W, Nessim A, Carling G, Liu B et al..  2025.  DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice.. Mol Neurodegener. 20(1):124.
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SHee, Hammock BD, Li H et al..  2025.  Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.. Mol Neurodegener. 20(1):44.
Marks K, Ahn S-J, Rai N, Anfray A, Iadecola C, Anrather J.  2025.  A minimally invasive thrombotic model to study stroke in awake mice.. Nat Commun. 16(1):4356.
Ahn S-J, Goya B, Bertomo C, Sciortino R, Racchumi G, Bonilla LGarcia, Anrather J, Iadecola C, Faraco G.  2025.  Neutrophil stalling does not mediate the increase in tau phosphorylation and the cognitive impairment associated with high salt diet.. Cardiovasc Res. 121(16):2578-2593.
Mossa A, Dierdorff L, Lukin J, Garcia-Forn M, Wang W, Mamashli F, Park Y, Fiorenzani C, Akpinar Z, Kamps J et al..  2025.  Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X.. Nat Commun. 16(1):4512.
Blackmon TJ, MacMahon JA, Bernardino PN, Hogans RE, Cheng M-Y, Vu J, Lee RDiana, Saito NH, Grodzki ACristina, Bruun DA et al..  2025.  Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication.. Acta Neuropathol Commun. 13(1):62.
2024
Garcia-Bonilla L, Shahanoor Z, Sciortino R, Nazarzoda O, Racchumi G, Iadecola C, Anrather J.  2024.  Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke.. Nat Immunol. 25(2):357-370.
Bravo CParra, Krukowski K, Barker S, Wang C, Li Y, Fan L, Vázquez-Rosa E, Shin M-K, Wong MYing, McCullough LD et al..  2024.  Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.. Mol Neurodegener. 19(1):51.
Nelson AT, Cicardi MElena, Markandaiah SS, Han JYs, Philp NJ, Welebob E, Haeusler AR, Pasinelli P, Manfredi G, Kawamata H et al..  2024.  Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes.. EMBO Rep. 25(5):2479-2510.
Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y et al..  2024.  KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.. J Clin Invest. 134(3)
Ávila-Gómez P, Shingai Y, Dash S, Liu C, Callegari K, Meyer H, Khodarkovskaya A, Aburakawa D, Uchida H, Faraco G et al..  2024.  Molecular and Functional Alterations in the Cerebral Microvasculature in an Optimized Mouse Model of Sepsis-Associated Cognitive Dysfunction.. eNeuro. 11(9)
Lopez-Lee C, Kodama L, Fan L, Zhu D, Zhu J, Wong MYing, Ye P, Norman K, Foxe NR, Ijaz L et al..  2024.  Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.. Science. 386(6725):eadk7844.
Uekawa K, Anfray A, Ahn SJi, Casey N, Seo J, Zhou P, Iadecola C, Park L.  2024.  tPA supplementation preserves neurovascular and cognitive function in Tg2576 mice.. Alzheimers Dement. 20(7):4572-4582.
2023
Das M, Mao W, Voskobiynyk Y, Necula D, Lew I, Petersen C, Zahn A, Yu G-Q, Yu X, Smith N et al..  2023.  Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.. Neurobiol Dis. 186:106263.
Pacholko AG, Bekar LK.  2023.  Different pharmacokinetics of lithium orotate inform why it is more potent, effective, and less toxic than lithium carbonate in a mouse model of mania.. J Psychiatr Res. 164:192-201.
Naguib S, Backstrom JR, Artis E, Ghose P, Stahl A, Hardin R, Haider AA, Ang J, Calkins DJ, Rex TS.  2023.  NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells.. Acta Neuropathol Commun. 11(1):171.
2022
Burré J, Sharma M.  2022.  Cellular And Small Animal Models Of Neurodegenerative Diseases.. J Vis Exp. (186)
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK et al..  2022.  Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.. Mol Neurodegener. 17(1):41.
Yan Y, Wang X, Chaput D, Shin M-K, Koh Y, Gan L, Pieper AA, Woo J-AA, Kang DE.  2022.  X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women.. Cell. 185(21):3913-3930.e19.
2019
Moda-Sava RN, Murdock MH, Parekh PK, Fetcho RN, Huang BS, Huynh TN, Witztum J, Shaver DC, Rosenthal DL, Alway EJ et al..  2019.  Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.. Science. 364(6436)
2017
Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA.  2017.  D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome.. PLoS One. 12(8):e0183026.