Feil Family Brain & Mind Research Institute

Publications

Found 9 results
Author Title Type [ Year(Asc)]
Filters: Keyword is Amyotrophic Lateral Sclerosis  [Clear All Filters]
2025
Larrea D, Tamucci KA, Kabra K, Velasco KR, Yun TD, Pera M, Montesinos J, Agrawal RR, Paradas C, Smerdon JW et al..  2025.  Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS).. Nat Commun. 16(1):379.
Woo E, Tasnim F, Kawamata H, Manfredi G, Konrad C.  2025.  Investigation of mitochondrial phenotypes in motor neurons derived by direct conversion of fibroblasts from familial ALS subjects.. Cell Death Dis. 17(1):51.
2024
Nelson AT, Cicardi MElena, Markandaiah SS, Han JYs, Philp NJ, Welebob E, Haeusler AR, Pasinelli P, Manfredi G, Kawamata H et al..  2024.  Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes.. EMBO Rep. 25(5):2479-2510.
2023
Li J, Jaiswal MK, Chien J-F, Kozlenkov A, Jung J, Zhou P, Gardashli M, Pregent LJ, Engelberg-Cook E, Dickson DW et al..  2023.  Divergent single cell transcriptome and epigenome alterations in ALS and FTD patients with C9orf72 mutation.. Nat Commun. 14(1):5714.
Woo E, Bredvik K, Liu B, Fuchs TJ, Manfredi G, Konrad C.  2023.  Machine learning approaches based on fibroblast morphometry do not predict ALS.. Neurobiol Aging. 130:80-83.
2017
Fil D, DeLoach A, Yadav S, Alkam D, MacNicol M, Singh A, Compadre CM, Goellner JJ, O'Brien CA, Fahmi T et al..  2017.  Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.. Hum Mol Genet. 26(4):686-701.
2016
Manfredi G, Kawamata H.  2016.  Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.. Neurobiol Dis. 90:35-42.
Esmaeili MA, Yadav S, Gupta RKr, Waggoner GR, DeLoach A, Calingasan NY, M Beal F, Kiaei M.  2016.  Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.. Hum Mol Genet. 25(2):317-27.
2015
Jackson KL, Dayton RD, Orchard EA, Ju S, Ringe D, Petsko GA, Maquat LE, Klein RL.  2015.  Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis.. Gene Ther. 22(1):20-8.