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Found 11 results
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alpha-Synuclein
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2023
Lai Y
,
Zhao C
,
Tian Z
,
Wang C
,
Fan J
,
Hu X
,
Tu J
,
Li T
,
Leitz J
,
Pfuetzner RA
et al.
. 2023.
Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering.
.
Proc Natl Acad Sci U S A. 120(44):e2310174120.
Chlebowicz J
,
Russ W
,
Chen D
,
Vega A
,
Vernino S
,
White CL
,
Rizo J
,
Joachimiak LA
,
Diamond MI
. 2023.
Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation.
.
Sci Adv. 9(43):eadh3457.
Sharma M
,
Burré J
. 2023.
α-Synuclein in synaptic function and dysfunction.
.
Trends Neurosci. 46(2):153-166.
2022
Xie YXue
,
Naseri NN
,
Fels J
,
Kharel P
,
Na Y
,
Lane D
,
Burré J
,
Sharma M
. 2022.
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
.
Nat Commun. 13(1):4918.
Carnazza KE
,
Komer LE
,
Xie YXue
,
Pineda A
,
Briano JAntonio
,
Gao V
,
Na Y
,
Ramlall T
,
Buchman VL
,
Eliezer D
et al.
. 2022.
Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins.
.
Cell Rep. 39(2):110675.
2018
Burré J
,
Sharma M
,
Südhof TC
. 2018.
Cell Biology and Pathophysiology of α-Synuclein.
.
Cold Spring Harb Perspect Med. 8(3)
2017
Pineda A
,
Burré J
. 2017.
Modulating membrane binding of α-synuclein as a therapeutic strategy.
.
Proc Natl Acad Sci U S A. 114(6):1223-1225.
Kawamata H
,
Manfredi G
. 2017.
Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.
.
J Cell Biol. 216(12):3917-3929.
Tapias V
,
Hu X
,
Luk KC
,
Sanders LH
,
Lee VM
,
J Greenamyre T
. 2017.
Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production.
.
Cell Mol Life Sci. 74(15):2851-2874.
2016
Chung SYoung
,
Kishinevsky S
,
Mazzulli JR
,
Graziotto J
,
Mrejeru A
,
Mosharov EV
,
Puspita L
,
Valiulahi P
,
Sulzer D
,
Milner TA
et al.
. 2016.
Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation.
.
Stem Cell Reports. 7(4):664-677.
2015
Burré J
,
Sharma M
,
Südhof TC
. 2015.
Definition of a molecular pathway mediating α-synuclein neurotoxicity.
.
J Neurosci. 35(13):5221-32.