Feil Family Brain & Mind Research Institute

Publications

Found 52 results
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2025
Zheng H, Feng Y, Tang J, Yu F, Wang Z, Xu J, Hai C, Jiang M, Cheng Y, Shao Z et al..  2025.  Astrocyte-secreted cues promote neural maturation and augment activity in human forebrain organoids.. Nat Commun. 16(1):2845.
Li D, Li J, Johann DJ, Butler D, Chen G, Foox J, Gong B, Jones W, Kreil DP, Kusko R et al..  2025.  Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations.. NPJ Precis Oncol. 9(1):182.
Birnbaum EM, Xie L, Serrano P, Rockwell P, Figueiredo-Pereira ME.  2025.  BT-11 targets the LANCL2 pathway to attenuate cognitive deficits and hippocampal pathology in Alzheimer's transgenic rats.. Sci Rep. 16(1):1848.
Hu W, Foord C, Hsu J, Fan L, Corley MJ, Lanjewar SN, Xu S, Belchikov N, He Y, Pang APS et al..  2025.  Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state.. Nat Biotechnol.
Patra S, Namballa HK, Gudipally AR, Xie L, Xie L, Harding WW.  2025.  Discovery of a selective α2C-AR scaffold from a molecular hybridization approach.. Bioorg Med Chem. 131:118424.
Patra S, Namballa HK, Gudipally AR, Xie L, Xie L, Harding WW.  2025.  Discovery of a selective α2C-AR scaffold from a molecular hybridization approach.. Bioorg Med Chem. 131:118424.
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SHee, Hammock BD, Li H et al..  2025.  Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.. Mol Neurodegener. 20(1):44.
Mottaqi M, Zhang P, Xie L.  2025.  Integrating explainable artificial intelligence with multiomics systems biology and electronic health record data mining for personalized drug repurposing in Alzheimer's disease.. Brief Bioinform. 26(6)
Zhang Y-L, Ding S-X, Cao M, Zhang S-Y, Li Y, Wang Z, Jin Y-X, Chen S-J, Wang Y-M, Marshall C et al..  2025.  Lung memory B cells ameliorate Alzheimer's disease-like pathology in 5×FAD mice through the CXCL12-CXCR4 axis.. Acta Pharmacol Sin.
Ding S, Chen S, Jin Y, Li Y, Wang Y, Wang Y, Zhang S, Pang Y, Wang Z, Feng W et al..  2025.  Meningeal macrophages alleviate social memory defects in an early Alzheimer's disease model.. Mol Psychiatry.
Barnett D, Zimmer TS, Booraem C, Palaguachi F, Meadows SM, Xiao H, Wong MYing, Luo W, Gan L, Chouchani ET et al..  2025.  Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.. Nat Metab. 7(11):2300-2323.
Celii B, Papadopoulos S, Ding Z, Fahey PG, Wang E, Papadopoulos C, Kunin AB, Patel S, J Bae A, Bodor AL et al..  2025.  NEURD offers automated proofreading and feature extraction for connectomics.. Nature. 640(8058):487-496.
2024
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.
Carling GK, Fan L, Foxe NR, Norman K, Wong MYing, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. Neuron.
Guiberson NGuy Lewis, Black LS, Haller JE, Brukner A, Abramov D, Ahmad S, Xie YXin, Sharma M, Burré J.  2024.  Disease-linked mutations in Munc18-1 deplete synaptic Doc2.. Brain.
Zheng X, Wu B, Liu Y, Simmons SK, Kim K, Clarke GS, Ashiq A, Park J, Li J, Wang Z et al..  2024.  Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development.. Cell.
Wang C, Zhao C, Xiao H, Qiang J, Liu Z, Gu J, Zhang S, Li D, Zhang Y, Burré J et al..  2024.  N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine.. Elife. 13
Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR et al..  2024.  Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.. PNAS Nexus. 3(5):pgae179.
Feng W, Zhang Y, Wang Z, Wang T, Pang Y, Li Y, Wang Y, Ding S, Chen S, Zou Y et al..  2024.  Protocol for evaluating mutualistic cooperative behavior in mice using a water-reward task assay.. STAR Protoc. 5(2):103023.
Fazal S, Danzi MC, Xu I, Kobren SNadimpalli, Sunyaev S, Reuter C, Marwaha S, Wheeler M, Dolzhenko E, Lucas F et al..  2024.  RExPRT: a machine learning tool to predict pathogenicity of tandem repeat loci.. Genome Biol. 25(1):39.
Carnazza KE, Komer LE, Xie YXue, Pineda A, Briano JAntonio, Gao V, Na Y, Ramlall T, Buchman VL, Eliezer D et al..  2024.  Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins.. Cell Rep. 43(5):114280.
Gong B, Li D, Łabaj PP, Pan B, Novoradovskaya N, Thierry-Mieg D, Thierry-Mieg J, Chen G, Lucas ABergstrom, LoCoco JS et al..  2024.  Targeted DNA-seq and RNA-seq of Reference Samples with Short-read and Long-read Sequencing.. Sci Data. 11(1):892.
Gong B, Li D, Łabaj PP, Pan B, Novoradovskaya N, Thierry-Mieg D, Thierry-Mieg J, Chen G, Lucas ABergstrom, LoCoco JS et al..  2024.  Targeted DNA-seq and RNA-seq of Reference Samples with Short-read and Long-read Sequencing.. Sci Data. 11(1):892.
2023
Dorkenwald S, Schneider-Mizell CM, Brittain D, Halageri A, Jordan C, Kemnitz N, Castro MA, Silversmith W, Maitin-Shephard J, Troidl J et al..  2023.  CAVE: Connectome Annotation Versioning Engine.. bioRxiv.
Ding W, Stohl LL, Xu L, Zhou XK, Manni M, Wagner JA, Granstein RD.  2023.  Correction: Calcitonin Gene-Related Peptide-Exposed Endothelial Cells Bias Antigen Presentation to CD4+ T Cells toward a Th17 Response.. J Immunol.