Publications

Found 267 results
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2025
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.. Immunity.
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.. Immunity.
Kohno S, Okahashi N, Wan Y, Yu H, Takegami Y, Linn P, Nagatani N, Kitajima S, Kawada T, Matsuda F et al..  2025.  RB1 controls differentiation through positive regulation of phosphoglycerate mutases.. Cell Death Dis. 16(1):559.
Foord C, Prjibelski AD, Hu W, Michielsen L, Vandelli A, Narykov O, Evans B, Hsu J, Belchikov N, Jarroux J et al..  2025.  A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.. Nat Commun. 16(1):8093.
Breves SL, Di Giammartino DCampigli, Nicholson J, Cirigliano S, Mahmood SRaza, Lee UJin, Martinez-Fundichely A, Jungverdorben J, Singhania R, Rajkumar S et al..  2025.  Three-dimensional regulatory hubs support oncogenic programs in glioblastoma.. Mol Cell. 85(7):1330-1348.e6.
Weis MA, Papadopoulos S, Hansel L, Lüddecke T, Celii B, Fahey PG, Wang EY, J Bae A, Bodor AL, Brittain D et al..  2025.  An unsupervised map of excitatory neuron dendritic morphology in the mouse visual cortex.. Nat Commun. 16(1):3361.
2024
Kloske CM, Belloy ME, Blue EE, Bowman GR, Carrillo MC, Chen X, Chiba-Falek O, Davis AA, Di Paolo G, Garretti F et al..  2024.  Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.. Alzheimers Dement.
Kloske CM, Belloy ME, Blue EE, Bowman GR, Carrillo MC, Chen X, Chiba-Falek O, Davis AA, Di Paolo G, Garretti F et al..  2024.  Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.. Alzheimers Dement.
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.
Carling GK, Fan L, Foxe NR, Norman K, Wong MYing, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. Neuron.
Garcia-Bonilla L, Shahanoor Z, Sciortino R, Nazarzoda O, Racchumi G, Iadecola C, Anrather J.  2024.  Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke.. Nat Immunol. 25(2):357-370.
Parikh NS, Zhang C, Bruce SS, Murthy SB, Rosenblatt R, Liberman AL, Liao V, Kaiser JH, Navi BB, Iadecola C et al..  2024.  Association between elevated fibrosis-4 index of liver fibrosis and risk of hemorrhagic stroke.. Eur Stroke J. :23969873241259561.
Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S-Y, Li X, Christensen T, Salisbury JL, Geroux RE, Gateno B et al..  2024.  Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice.. Commun Biol. 7(1):234.
Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S-Y, Li X, Christensen T, Salisbury JL, Geroux RE, Gateno B et al..  2024.  Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice.. Commun Biol. 7(1):234.
Pfau SJ, Langen UH, Fisher TM, Prakash I, Nagpurwala F, Lozoya RA, Lee W-CAllen, Wu Z, Gu C.  2024.  Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells.. Nat Neurosci. 27(10):1892-1903.
Sayles NM, Napierala JS, Anrather J, Diedhiou N, Li J, Napierala M, Puccio H, Manfredi G.  2024.  Correction: Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.. Dis Model Mech. 17(1)
Sayles NM, Napierala JS, Anrather J, Diedhiou N, Li J, Napierala M, Puccio H, Manfredi G.  2024.  Correction: Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.. Dis Model Mech. 17(1)
Yoval-Sánchez B, Guerrero I, Ansari F, Niatsetskaya Z, Siragusa M, Magrane J, Ten V, Konrad C, Szibor M, Galkin A.  2024.  Effect of alternative oxidase (AOX) expression on mouse cerebral mitochondria bioenergetics.. Redox Biol. 77:103378.
Buth JE, Dyevich CE, Rubin A, Wang C, Gao L, Marks T, Harrison MRm, Kong JH, M Ross E, Novitch BG et al..  2024.  Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance.. EMBO Rep.
Nelson AT, Cicardi MElena, Markandaiah SS, Han JYs, Philp NJ, Welebob E, Haeusler AR, Pasinelli P, Manfredi G, Kawamata H et al..  2024.  Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes.. EMBO Rep. 25(5):2479-2510.
Theofilas P, Wang C, Butler D, Morales DO, Petersen C, Ambrose A, Chin B, Yang T, Khan S, Ng R et al..  2024.  iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death.. Mol Cell Neurosci. 130:103954.
Knepp B, Navi BB, Rodriguez F, DeAngelis LM, Elkind MSV, Iadecola C, Sherman CP, Tagawa ST, Saxena A, Ocean AJ et al..  2024.  Ischemic Stroke with Comorbid Cancer Has Specific miRNA-mRNA Networks in Blood That Vary by Ischemic Stroke Mechanism.. Ann Neurol. 96(3):565-581.
Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y et al..  2024.  KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.. J Clin Invest. 134(3)
Kudo R, Safonov A, Jones C, Moiso E, Dry JR, Shao H, Nag S, da Silva EM, Yildirim SYeni, Li Q et al..  2024.  Long-term breast cancer response to CDK4/6 inhibition defined by TP53-mediated geroconversion.. Cancer Cell. 42(11):1919-1935.e9.
Kudo R, Safonov A, Jones C, Moiso E, Dry JR, Shao H, Nag S, da Silva EM, Yildirim SYeni, Li Q et al..  2024.  Long-term breast cancer response to CDK4/6 inhibition defined by TP53-mediated geroconversion.. Cancer Cell. 42(11):1919-1935.e9.