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Found 22 results
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Luo, Wenjie
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Journal Article
Yuan P
,
Condello C
,
C Keene D
,
Wang Y
,
Bird TD
,
Paul SM
,
Luo W
,
Colonna M
,
Baddeley D
,
Grutzendler J
. 2016.
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
.
Neuron. 90(4):724-39.
Hu X
,
Li X
,
Zhao M
,
Gottesdiener A
,
Luo W
,
Paul S
. 2014.
Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.
.
Mol Neurodegener. 9:52.
Tracy TE
,
Madero-Pérez J
,
Swaney DL
,
Chang TS
,
Moritz M
,
Konrad C
,
Ward ME
,
Stevenson E
,
Hüttenhain R
,
Kauwe G
et al.
. 2022.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
.
Cell. 185(4):712-728.e14.
Hardwick SA
,
Hu W
,
Joglekar A
,
Fan L
,
Collier PG
,
Foord C
,
Balacco J
,
Lanjewar S
,
Sampson MMcGuirk
,
Koopmans F
et al.
. 2022.
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue.
.
Nat Biotechnol.
Gupta I
,
Collier PG
,
Haase B
,
Mahfouz A
,
Joglekar A
,
Floyd T
,
Koopmans F
,
Barres B
,
Smit AB
,
Sloan SA
et al.
. 2018.
Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells.
.
Nat Biotechnol.
Lopez-Lee C
,
Kodama L
,
Fan L
,
Wong MYing
,
Foxe NR
,
Jiaz L
,
Yu F
,
Ye P
,
Zhu J
,
Norman K
et al.
. 2023.
Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging.
.
bioRxiv.
Du H
,
Wong MYing
,
Zhang T
,
Santos MNunez
,
Hsu C
,
Zhang J
,
Yu H
,
Luo W
,
Hu F
. 2021.
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
.
Life Sci Alliance. 4(7)
Wang C
,
Fan L
,
Khawaja RR
,
Liu B
,
Zhan L
,
Kodama L
,
Chin M
,
Li Y
,
Le D
,
Zhou Y
et al.
. 2022.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
.
Nat Commun. 13(1):1969.
Luo W
,
Liu W
,
Hu X
,
Hanna M
,
Caravaca A
,
Paul SM
. 2015.
Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.
.
Sci Rep. 5:11161.
Bravo CParra
,
Giani AMaria
,
Perez JMadero
,
Zhao Z
,
Wan Y
,
Samelson AJ
,
Wong MYing
,
Evangelisti A
,
Cordes E
,
Fan L
et al.
. 2024.
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
.
Cell.
Bravo CParra
,
Giani AMaria
,
Perez JMadero
,
Zhao Z
,
Samelson A
,
Wong MYing
,
Evangelisti A
,
Fan L
,
Pozner T
,
Mercedes M
et al.
. 2023.
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
.
bioRxiv.
Lee D
,
Lee W-S
,
Lim S
,
Kim YKyung
,
Jung H-Y
,
Das S
,
Lee J
,
Luo W
,
Kim K-T
,
Chung S-K
. 2017.
A guanidine-appended scyllo-inositol derivative AAD-66 enhances brain delivery and ameliorates Alzheimer's phenotypes.
.
Sci Rep. 7(1):14125.
Xu P
,
Chang JC
,
Zhou X
,
Wang W
,
Bamkole M
,
Wong E
,
Bettayeb K
,
Jiang L-L
,
Huang T
,
Luo W
et al.
. 2021.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
.
J Exp Med. 218(8)
Yang X
,
Wen J
,
Yang H
,
Jones IR
,
Zhu X
,
Liu W
,
Li B
,
Clelland CD
,
Luo W
,
Wong MYing
et al.
. 2023.
Functional characterization of Alzheimer's disease genetic variants in microglia.
.
Nat Genet. 55(10):1735-1744.
Chen H
,
Fan L
,
Guo Q
,
Wong MYing
,
Yu F
,
Foxe N
,
Wang W
,
Nessim A
,
Carling G
,
Liu B
et al.
. 2023.
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
.
Res Sq.
Chen H
,
Fan L
,
Guo Q
,
Wong MYing
,
Yu F
,
Foxe N
,
Wang W
,
Nessim A
,
Carling G
,
Liu B
et al.
. 2023.
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
.
bioRxiv.
Uekawa K
,
Hattori Y
,
Ahn SJi
,
Seo J
,
Casey N
,
Anfray A
,
Zhou P
,
Luo W
,
Anrather J
,
Park L
et al.
. 2023.
Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress.
.
Mol Neurodegener. 18(1):73.
Cao J
,
Gaamouch FEl
,
Meabon JS
,
Meeker KD
,
Zhu L
,
Zhong MB
,
Bendik J
,
Elder G
,
Jing P
,
Xia J
et al.
. 2017.
ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.
.
Sci Rep. 7(1):11372.
Shi Y
,
Yamada K
,
Liddelow SAntony
,
Smith ST
,
Zhao L
,
Luo W
,
Tsai RM
,
Spina S
,
Grinberg LT
,
Rojas JC
et al.
. 2017.
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
.
Nature. 549(7673):523-527.
Carling GK
,
Fan L
,
Foxe NR
,
Norman K
,
Ye P
,
Wong MYing
,
Zhu D
,
Yu F
,
Xu J
,
Yarahmady A
et al.
. 2024.
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
.
bioRxiv.
Luo W
,
Qu W
,
Gan L
. 2023.
The AD odyssey 2023: Tales of single cell.
.
Cell. 186(20):4257-4259.
Wong MYing
,
Lewis M
,
Doherty JJ
,
Shi Y
,
Cashikar AG
,
Amelianchik A
,
Tymchuk S
,
Sullivan PM
,
Qian M
,
Covey DF
et al.
. 2020.
25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.
.
J Neuroinflammation. 17(1):192.