Feil Family Brain & Mind Research Institute

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New Grants

Academic Year 2018

Laibaik Park (PI)
NINDS 1R01NS097805-01A1
tPA and cerebrovascular regulation in a model of ß-amyloid pathology

Santosh Murthy (PI)
NINDS 1K23NS105948-01
Intracerebral Hemorrhage and Increased Risk of Arterial Thromboembolism

Dilek Colak (PI)
NIMH 1R01MH114888-01A1
Local mRNA degradation in GluR1 signaling, synaptic plasticity, and cognitive
function

Academic Year 2017

Jordi Magrane (PI)
The Friedreich’s Ataxia Research Alliance (FARA)
Functional analysis of primary sensory neurons and (proprio) sensory pathology
in Friedreich’s ataxia

Virginia Pickel (PI)
NIH grant R01DA042943
Aberrant prefrontal cortical plasticity and neurobehavioral consequences of adolescent marijuana

Thu Huynh (PI)
NARSAD; 1F32MH115654-01
Prefrontal microcircuit mechanisms underlying extinction memory formation

Timothy Vartanian
(PI)
NINDS 1R01NS104350-01
Damage Associated Molecular Patterns and Regenerative Failure in MS

Timothy Spellman (PI)
NARSAD 
Prefrontal Circuits Supporting Attentional Control

Anna Orr (PI)
Alzheimer's Association
Defining astrocytic-neuronal transcriptional alterations in memory loss

Keith Purpura (PI)
National Eye Institute  1R21EY028336-01
Processing of spatial information in V1 through fixational eye movements

Anna Goldschmidt Orr (PI)
NATIONAL INSTITUTE ON AGING   4R00AG048222-03
Roles of Astrocytic G Protein-Coupled Signaling in Memory

Teresa Milner (PI)
NIDA  1T32DA039080-01A1
Genetic and Environmental Influences on Addiction

Michael Glass (PI)
NIH  1R01HL135498-01A1 
Hypothalamic cytokines, glutamate receptor plasticity, and blood pressure

Nicholas Schiff (PI)
Daedalus Fund
Dynamic Multi-lead Deep Brain Stimulation of the Central Thalamus to Treat Chronic Cognitive Deficts in Severe-to-Moderate Traumatic Brain injured Patients

Conor Liston (PI)
Rita Allen Foundation
Prefrontal Circuit Mechanisms for Encoding Working Memory in Hyperexcitable Brain States

Jennifer Linden (PI)
National Multiple Sclerosis Society
Using Endothelial Microparticles to Study Real-Time Blood Brain Barrier Permeability in Multiple Sclerosis Patients

Gregory Petsko (PI)
Target ALS Foundation
Gene Therapeutic modulation of NMD for treatment of ALS

Hooman Kamel (PI)
NIH (Columbia)  1U01NS095869-01A1
AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenicstroke (ARCADIA)

Michael J. Glass (MPI)
Teresa A. Milner (MPI)
NHLBI  1R01HL136520-01
Contribution of estrogen receptor beta to changes in hypothalamic plasticity and hypertension susceptibility in mice with accelerated ovarian failure

Natalia De Marco Garcia (PI)
Frueauff Foundation Award
A in vivo approach to detect interneuron dysfunction in neurodevelopmental disorders

Jacqueline Burre (PI)
NINDS   1R01NS102181-01  
Molecular mechanisms of Munc18-1 linked infantile seizure disorders and rational rescue strategies

Manu Sharma (PI)
NINDS  1R01NS095988-01A1
Cellular mechanism of Adult Onset Neuronal Ceroid Lipofuscinosis (ANCL) caused by mutations in cysteine string protein-alpha (CSPalpha).

Anatoly Starkov (PI)
NIH (Columbia Sub)
Mitochondrial complex-I as a target for metabolic resuscitation in perinatal hypoxicischemic brain injury

Academic Year 2016

Margaret Elizabeth Ross (PI)
NIH/NICHD 2P01HD067244-06
Risk Genes and Environmental Interactions in Neural Tube Defects

Costantino Iadecola  (PI)
NIH/NINDS 1R01NS100447-01
​ApoE4 and mechanisms of diffuse white matter injury 

Daniel J Thengone (PI)
NIH/NEI F31EY025535
Neuronal interactions during sensory adaptation 

Manu Sharma (PI)
NIH/NIA 1R01AG052505-01
DnaJ co-chaperones which modify tau aggregation and neurodegeneration

Natalia DeMarco (PI)
NIH/NIMH 1R01MH110553-01
Neural mechanism for the assembly of GABAergic circuits in the cerebral cortex

Hooman Kamel  (PI)
NIH/NINDS 1 R01 NS097443-01
Left Atrial abNormality, ThromboEmbolism, and Race: Novel risk factors for stroke (LANTERN)
 
Costantino Iadecola (Co-PI)
Giovanni Manfredi (Co-PI)
NIH/NINDS 1R01NS095692-01A1
Estrogen receptor beta and mitochondrial permeability transition in Ca2+ induced neuronal injury
 
Conor Liston (PI)
NIH/NIMH 1R01MH109685
Prefrontal cortical microcircuit mechanisms of working memory deficits in chronic stress

Wenjie Luo (PI)
BrightFocus Foundation
Retromer chaperone R33 selectively promotes Abeta degradation by microglia

Giovanni Manfredi (PI)
Muscular Dystrophy Association
CHCHD10 in familial ALS

 Jonathan Victor (PI)
National Science Foundation
Collaborative Research: Olfactory Navigation: Dynamic Computing in the Natural Environment

Costantino Iadecola (PI)
NIH/NINDS 1R01 NS095441
Dietary sodium, neurovascular dysfunction and cerebrovascular risk

M. Flint Beal (PI)
CURE Parkinson’s Disease
Preventing lipid peroxidation to rescue alpha-synuclein toxicity in vivo

Wenjie Luo (PI)
Sanofi Innovation Award
Search for small molecules promoting tau clearance by microglia

Natalia DeMarco (PI)
Citizens United for Research in Epilepsy
Regulation of cortical interneuron migration and epilepsy

Nicholas Schiff (PI)
NINDS BRAIN Initiative
Central thalamic stimulation for traumatic brain injury

Conor Liston (PI)
IMHRO Rising Star Award
Circuit biomarkers for diagnosing and treating neurophysiological subtypes of depression

 

Academic Year 2015

Manu Sharma (PI)
Alzheimer's Association
Tau Proteostasis by Cysteine String Protein-alpha (CSP-alpha)

Jonathan Victor (PI)
NIH R01EY007977 (competitive renewal)
Central Processing of Visual Information

Jacqueline Burre (PI)
American Parkinson's Disease Association
Aging increases the aggregation-prone cytosolic pool of alpha-synuclein

Manu Sharma (PI)
AFAR New Investigator Award in Alzheimer’s Disease Research
Tau Proteostasis by Hsc70 Co-Chaperones

Costantino Iadecola (PI) 
NIH 1R37NS089323 (Javits Award) 
Hypertension and neurovascular dysfunction  

Ping Zhou (PI)
NIH 5R01NS067078 (competitive renewal)
Role of Prohibitin in Ischemic Brain Injury 

Esteban Fridman (PI)
NIH 1R21NS093268
Specification of dopaminergic synaptic disorders severe brain injury 

Giovanni Manfredi (PI)
NIH 1R01NS093872
Metabolic profiling of sporadic ALS patients 

Teresa A. Milner (PI)
NIH 2R01 DA 008529-21 (competitive renewal)
Stress-opioid interaction in hippocampus

Conor Liston (PI)
Hartwell Foundation 
Neuroimaging biomarkers in autism spectrum disorders 

Makoto Ishii (PI
Bright Focus Foundation 
Pathological role of amyloid-beta on adipocyte hormone signaling

Jacqueline Burre (PI) 
The American Epilepsy Society and the Epilepsy Foundation
Dysfunction of STXBP1 in infantile epileptic encephalopathies

Jacqueline Burre (PI)
Leon Levy Foundation Grant
Function and Dysfunction of Synucleins at the Synapse

Wenjie Luo (PI)
Cart Foundation
Investigating the role of microglia in tau clearance in Alzheimer’s disease

Jordi Magrane (PI)
The Friedreich’s Ataxia Research Alliance (FARA)
Approaches to correct mitochondrial abnormalities and synaptic pathology in frataxin-deficient sensory neurons

 

Weill Cornell Medicine Feil Family Brain & Mind Research Institute 407 E 61st St New York, NY 10065 Phone: (646) 962-8277 Fax: (646) 962-0535