Nov 15 2019 - 12:00pm
Speaker: Makoto Ishii, MD, Ph.D., Assistant Professor of Neurology and Neuroscience, Department of Neurology and BMRI, WCM (B2B)
Location: Feil Family Research Building Conference Room 108
Nov 14 2019 - 4:00pm to 5:00pm
Location: Weill Auditorium
We have recently shown that brain capillaries act as a neural activity-sensing network by initiating and transmitting an electrical signal, mediated by potassium channel activation that propagates through the interconnected endothelial cells comprising the capillaries that line all blood vessels. This concept explains the rapid and coordinated delivery of blood to active neurons. Using a mouse model of a monogenic form of Singular Value Decomposition (SVD), we have discovered early defects that...
Nov 8 2019 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"Fostering Lysosomes to Treat Alzheimer’s Disease" Santiago Sole Domenech, Ph.D. Biochemistry Research Associate and Fellow Weill Cornell Medicine
Nov 8 2019 - 12:00pm
Speaker: Santiago Sole Domenech, Ph.D., Maxfield Laboratory, Research Associate in Biochemistry, Department of Biochemistry, WCM (Leon Levy Fellow)
Location: Feil Family Research Building Conference Room 108
Nov 7 2019 - 4:00pm to 5:00pm
Location: Weill Auditorium
Our group has a long-standing research program concerning the use of genetics as well as biochemical and behavioral approaches in the study of neurodegeneration with a focus on the human disease SpinoCerebellar Ataxia type 1 (SCA1). In collaboration with Huda Zoghbi at Baylor, we cloned the SCA1 gene - the first genetically defined ataxia. We went on to establish the first transgenic mouse model of a polyglutamine disease. This model is the center of continued studies on the normal function of...
Nov 1 2019 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"Molecular Neuroimaging as a Translational Tool for Traumatic Brain Injury (TBI) Drug Development" Esteban A. Fridman, M.D., Ph.D., Assistant Neuroscience Professor Weill Cornell Medicine (WCM) BMRI
Nov 1 2019 - 12:00pm
Speaker: Esteban A. Fridman, M.D., Ph.D., Assistant Professor of Neuroscience, BMRI, WCM
Oct 25 2019 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"Stabilization of Munc18-1 function via target-specific pharmacological chaperones identified through an in silico screen" Debra Abramov, Tri-institutional MD-Ph.D. candidate, Burre Laboratory, BMRI, WCM
Oct 25 2019 - 12:00pm
Speaker: Debra Abramov, Tri-institutional MD-Ph.D. candidate, Burre Laboratory, BMRI, WCM
Location: Feil Family Research Building Conference Room 108
Oct 24 2019 - 4:00pm to 5:00pm
Location: Weill Auditorium
Marta Filizola, Ph.D. Graduate School of Biomedical Sciences Dean and Professor With an average of 130 Americans dying every day, and opioid drugs still representing the gold standard for pain management, there is an urgent need to identify innovative solutions to prevent life-threatening opioid overdoses and treat opioid use disorders. Clinical opioid drugs inhibit nociceptive signaling but also cause respiratory depression by targeting a G-protein coupled receptor, specifically the µ-opioid...