| Title | CAR-A astrocytes for Alzheimer's: Promise and challenge. |
| Publication Type | Journal Article |
| Year of Publication | 2026 |
| Authors | Lee S-I, Luo W, Gan L |
| Journal | Cell Stem Cell |
| Volume | 33 |
| Issue | 5 |
| Pagination | 720-721 |
| Date Published | 2026 May 07 |
| ISSN | 1875-9777 |
| Keywords | Alzheimer Disease, Amyloid beta-Peptides, Animals, Astrocytes, Humans, Receptors, Chimeric Antigen |
| Abstract | In a recent study in Science, Chen et al. engineer astrocytes with anti-amyloid chimeric antigen receptors (CARs) to enable sustained, antigen-directed clearance of amyloid-β (Aβ) in vivo, revealing how CAR design can shape both pathology and glial responses. |
| DOI | 10.1016/j.stem.2026.04.008 |
| Alternate Journal | Cell Stem Cell |
| PubMed ID | 42102723 |