Babak B. Navi, MD, MS
Associate Professor of Neurology
Associate Professor of Neuroscience
Associate Director of the Clinical and Translational Neuroscience Unit
I am an academic neurologist with specialty training in stroke and clinical research, particularly epidemiological research. As a member of the Brain and Mind Research Institute, I conduct clinical trials, observational studies, and meta-analyses in order to advance our understanding of the risk factors and mechanisms of vascular disease in the brain. My primary research interest is the relationship between stroke and cancer—two common and morbid diseases with immense pubic health impacts.
My short-term goals are to determine why patients with cancer suffer stroke and how to best treat these patients to prevent recurrent stroke. I also plan to determine what the effects of cancer type, stage, and treatments are on patients’ stroke risk.
My long-term goal is to reduce the incidence and burden of stroke in patients with cancer. I plan to do this by elucidating the complex relationship between stroke and cancer, which will enable the identification and targeted treatment of cancer patients at high risk for stroke.
- I have published over 80 peer-reviewed articles on stroke, including many in top-tier journals, such as New England Journal of Medicine, JAMA, JACC, Annals of Neurology, JAMA Neurology, Stroke, and Neurology
- American Heart Association’s Young Heart Award, 2017
- National Institutes of Health K23 grant recipient, 2015
- Associate Editor for the Neurohospitalist journal, 2015-present
- Florence Gould Endowment for Discovery in Stroke recipient, 2014, 2017
- National Institutes of Health KL2 grant recipient, 2012
- Brain Attack and Cerebrovascular Disease Conference Co-Director, 2012-present
- Navi BB, Reichman JS, Berlin D, Reiner AS, Panageas KS, Segal AZ, DeAngelis LM. Intracerebral and subarachnoid hemorrhage in patients with cancer. Neurology. 2010;74:494-501.
- Kamel H, Navi BB, Nakagawa K, Hemphill JC, Ko N. Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: A meta-analysis of randomized clinical trials. Crit Care Med. 2011;39:554-559.
- Navi BB, Kamel H, McCulloch CE, Nakagawa K, Naravetla B, Moheet AM, Wong C, Johnston SC, Hemphill JC, Smith WS. Accuracy of neurovascular fellows’ prognostication of outcome after subarachnoid hemorrhage. Stroke. 2012;43:702-707
- Navi BB, Kamel H, Shah MP, Grossman AW, Wong C, Poisson SN, Whetstone WD, Josephson SA, Johnston SC, Kim AS. Application of the ABCD2 score to identify cerebrovascular causes of dizziness in the emergency department. Stroke. 2012;43:1484-1489.
- Kamel H, Navi BB, Fahimi J. National trends in ambulance use by patients with stroke, 1997-2008. JAMA 2012;307:1026-1028.
- Kamel H, Navi BB, Sriram N, Hovsepian DA, Devereux RB, Elkind MSV. Risk of a thrombotic event after the 6-week postpartum period. N Engl J Med. 2014;370:1307-1315.
- Navi BB, Singer S, Merkler AE, Cheng NT, Stone JB, Kamel H, Iadecola C, Elkind MSV, DeAngelis LM. Recurrent thromboembolic events after ischemic stroke in patients with cancer. Neurology. 2014;83:26-33.
- Navi BB, Singer S, Merkler AE, Cheng NT, Stone JB, Kamel H, Iadecola C, Elkind MSV, DeAngelis LM. Cryptogenic subtype predicts reduced survival among cancer patients with ischemic stroke. Stroke. 2014;45:2292-2297.
- Navi BB, Reiner AS, Kamel H, Iadecola C, Elkind MSV, Panageas KS, DeAngelis LM. Association between incident cancer and subsequent stroke. Ann Neurol. 2015;77:291-300.
- Parikh NS, Burch JE, Kamel H, DeAngelis LM, Navi BB. Recurrent thromboembolic events after ischemic stroke in patients with primary brain tumors. J Stroke Cerebrovasc Dis. 2017;26:2396-2403.
- Navi BB, Reiner AS, Kamel H, Iadecola C, Okin PM, Elkind MSV, Panageas KS, DeAngelis LM. Risk of arterial thromboembolism in patients with cancer. J Am Coll Cardiol. 2017;70:926-938.
- Navi BB, Marshall RS, Bobrow D, Singer S, Stone JB, DeSancho MT, DeAngelis LM. Enoxaparin versus Aspirin in Patients with Cancer and Ischemic Stroke: The TEACH Pilot Randomized Clinical Trial. JAMA Neurol. Epub ahead of print January 8, 2018.
I am also an Associate Member (Affiliate) at the Memorial Sloan Kettering Cancer Center.
Frequent collaborators within the college are Costantino Iadecola, Lisa DeAngelis, Hooman Kamel, Ajay Gupta, Amy Kuceyeski, and Alex Merkler.