Publications

Found 36 results
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Journal Article
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.
Shi Y, Yamada K, Liddelow SAntony, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC et al..  2017.  ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.. Nature. 549(7673):523-527.
Cao J, Gaamouch FEl, Meabon JS, Meeker KD, Zhu L, Zhong MB, Bendik J, Elder G, Jing P, Xia J et al..  2017.  ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.. Sci Rep. 7(1):11372.
Dorkenwald S, Schneider-Mizell CM, Brittain D, Halageri A, Jordan C, Kemnitz N, Castro MA, Silversmith W, Maitin-Shephard J, Troidl J et al..  2023.  CAVE: Connectome Annotation Versioning Engine.. bioRxiv.
Ding W, Stohl LL, Xu L, Zhou XK, Manni M, Wagner JA, Granstein RD.  2023.  Correction: Calcitonin Gene-Related Peptide-Exposed Endothelial Cells Bias Antigen Presentation to CD4+ T Cells toward a Th17 Response.. J Immunol.
Deglincerti A, Liu Y, Colak D, Hengst U, Xu G, Jaffrey SR.  2015.  Coupled local translation and degradation regulate growth cone collapse.. Nat Commun. 6:6888.
Telpoukhovskaia MA, Liu K, Sayed FA, Etchegaray JIker, Xie M, Zhan L, Li Y, Zhou Y, Le D, Bahr BA et al..  2020.  Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.. Sci Rep. 10(1):13688.
Guiberson NGuy Lewis, Black LS, Haller JE, Brukner A, Abramov D, Ahmad S, Xie YXin, Sharma M, Burré J.  2024.  Disease-linked mutations in Munc18-1 deplete synaptic Doc2.. Brain.
Ma Y, Sannino D, Linden JR, Haigh S, Zhao B, Grigg JB, Zumbo P, Dündar F, Butler DJ, Profaci CP et al..  2023.  Epsilon toxin-producing Clostridium perfringens colonize the MS gut and epsilon toxin overcomes immune privilege.. J Clin Invest.
Zook JM, Catoe D, McDaniel J, Vang L, Spies N, Sidow A, Weng Z, Liu Y, Mason CE, Alexander N et al..  2016.  Extensive sequencing of seven human genomes to characterize benchmark reference materials.. Sci Data. 3:160025.
Zook JM, Catoe D, McDaniel J, Vang L, Spies N, Sidow A, Weng Z, Liu Y, Mason CE, Alexander N et al..  2016.  Extensive sequencing of seven human genomes to characterize benchmark reference materials.. Sci Data. 3:160025.
Garg A, Hannan A, Wang Q, Collins T, Teng S, Bansal M, Zhong J, Xu K, Zhang X.  2018.  FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination.. PLoS Genet. 14(9):e1007660.
Sziraki A, Lu Z, Lee J, Banyai G, Anderson S, Abdulraouf A, Metzner E, Liao A, Banfelder J, Epstein A et al..  2023.  A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains.. Nat Genet.
Xu P, Chang JC, Zhou X, Wang W, Bamkole M, Wong E, Bettayeb K, Jiang L-L, Huang T, Luo W et al..  2021.  GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.. J Exp Med. 218(8)
Xu P, Chang JC, Zhou X, Wang W, Bamkole M, Wong E, Bettayeb K, Jiang L-L, Huang T, Luo W et al..  2021.  GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.. J Exp Med. 218(8)
Hawrylycz M, Martone ME, Ascoli GA, Bjaalie JG, Dong H-W, Ghosh SS, Gillis J, Hertzano R, Haynor DR, Hof PR et al..  2023.  A guide to the BRAIN Initiative Cell Census Network data ecosystem.. PLoS Biol. 21(6):e3002133.
Hawrylycz M, Martone ME, Ascoli GA, Bjaalie JG, Dong H-W, Ghosh SS, Gillis J, Hertzano R, Haynor DR, Hof PR et al..  2023.  A guide to the BRAIN Initiative Cell Census Network data ecosystem.. PLoS Biol. 21(6):e3002133.
Gilani AI, Chohan MO, Inan M, Schobel SA, Chaudhury NH, Paskewitz S, Chuhma N, Glickstein S, Merker RJ, Xu Q et al..  2014.  Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition.. Proc Natl Acad Sci U S A. 111(20):7450-5.
Xie YXue, Naseri NN, Fels J, Kharel P, Na Y, Lane D, Burré J, Sharma M.  2022.  Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.. Nat Commun. 13(1):4918.
Zheng X, Wu B, Liu Y, Simmons SK, Kim K, Clarke GS, Ashiq A, Park J, Li J, Wang Z et al..  2024.  Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development.. Cell.
Kuo S-H, Tasset I, Cheng MM, Diaz A, Pan M-K, Lieberman OJ, Hutten SJ, Alcalay RN, Kim S, Ximénez-Embún P et al..  2022.  Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.. Sci Adv. 8(6):eabm6393.
Celii B, Papadopoulos S, Ding Z, Fahey PG, Wang E, Papadopoulos C, Kunin AB, Patel S, J Bae A, Bodor AL et al..  2023.  NEURD: automated proofreading and feature extraction for connectomics.. bioRxiv.
Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR et al..  2024.  Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.. PNAS Nexus. 3(5):pgae179.
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK et al..  2022.  Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.. Mol Neurodegener. 17(1):41.
Sohn PDongmin, Huang CTzu-Ling, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok S-A, Freilich R et al..  2019.  Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.. Neuron. 104(3):458-470.e5.