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Found 30 results
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Disease Models, Animal
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2014
Gilani AI
,
Chohan MO
,
Inan M
,
Schobel SA
,
Chaudhury NH
,
Paskewitz S
,
Chuhma N
,
Glickstein S
,
Merker RJ
,
Xu Q
et al.
. 2014.
Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition.
.
Proc Natl Acad Sci U S A. 111(20):7450-5.
Hu X
,
Li X
,
Zhao M
,
Gottesdiener A
,
Luo W
,
Paul S
. 2014.
Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.
.
Mol Neurodegener. 9:52.
Ishii M
,
Wang G
,
Racchumi G
,
Dyke JP
,
Iadecola C
. 2014.
Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.
.
J Neurosci. 34(27):9096-106.
2015
Ishii M
,
Iadecola C
. 2015.
Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology.
.
Cell Metab. 22(5):761-76.
Ma Q
,
Yang J
,
Li T
,
Milner TA
,
Hempstead BL
. 2015.
Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease.
.
Neurobiol Dis. 82:466-477.
Van Kempen TA
,
Dodos M
,
Woods C
,
Marques-Lopes J
,
Justice NJ
,
Iadecola C
,
Pickel VM
,
Glass MJ
,
Milner TA
. 2015.
Sex differences in NMDA GluN1 plasticity in rostral ventrolateral medulla neurons containing corticotropin-releasing factor type 1 receptor following slow-pressor angiotensin II hypertension.
.
Neuroscience. 307:83-97.
Hochrainer K
,
Jackman K
,
Benakis C
,
Anrather J
,
Iadecola C
. 2015.
SUMO2/3 is associated with ubiquitinated protein aggregates in the mouse neocortex after middle cerebral artery occlusion.
.
J Cereb Blood Flow Metab. 35(1):1-5.
2016
Van Kempen TA
,
Narayan A
,
Waters EM
,
Marques-Lopes J
,
Iadecola C
,
Glass MJ
,
Pickel VM
,
Milner TA
. 2016.
Alterations in the subcellular distribution of NADPH oxidase p47(phox) in hypothalamic paraventricular neurons following slow-pressor angiotensin II hypertension in female mice with accelerated ovarian failure.
.
J Comp Neurol. 524(11):2251-65.
Rau KK
,
Hill CE
,
Harrison BJ
,
Venkat G
,
Koenig HM
,
Cook SB
,
Rabchevsky AG
,
Taylor BK
,
Hai T
,
Petruska JC
. 2016.
Cutaneous tissue damage induces long-lasting nociceptive sensitization and regulation of cellular stress- and nerve injury-associated genes in sensory neurons.
.
Exp Neurol. 283(Pt A):413-27.
Chandra A
,
Sharma A
,
Calingasan NY
,
White JM
,
Shurubor Y
,
X Yang W
,
M Beal F
,
Johri A
. 2016.
Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease.
.
Hum Mol Genet. 25(11):2269-2282.
Zhao L
,
Gottesdiener AJ
,
Parmar M
,
Li M
,
Kaminsky SM
,
Chiuchiolo MJ
,
Sondhi D
,
Sullivan PM
,
Holtzman DM
,
Crystal RG
et al.
. 2016.
Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
.
Neurobiol Aging. 44:159-172.
McGuire MJ
,
Ishii M
. 2016.
Leptin Dysfunction and Alzheimer's Disease: Evidence from Cellular, Animal, and Human Studies.
.
Cell Mol Neurobiol. 36(2):203-17.
Lee AS
,
De Jesús-Cortés H
,
Kabir ZD
,
Knobbe W
,
Orr M
,
Burgdorf C
,
Huntington P
,
McDaniel L
,
Britt JK
,
Hoffmann F
et al.
. 2016.
The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons.
.
eNeuro. 3(2)
Esmaeili MA
,
Yadav S
,
Gupta RKr
,
Waggoner GR
,
DeLoach A
,
Calingasan NY
,
M Beal F
,
Kiaei M
. 2016.
Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.
.
Hum Mol Genet. 25(2):317-27.
Garcia-Bonilla L
,
Faraco G
,
Moore J
,
Murphy M
,
Racchumi G
,
Srinivasan J
,
Brea D
,
Iadecola C
,
Anrather J
. 2016.
Spatio-temporal profile, phenotypic diversity, and fate of recruited monocytes into the post-ischemic brain.
.
J Neuroinflammation. 13(1):285.
Yuan P
,
Condello C
,
C Keene D
,
Wang Y
,
Bird TD
,
Paul SM
,
Luo W
,
Colonna M
,
Baddeley D
,
Grutzendler J
. 2016.
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
.
Neuron. 90(4):724-39.
Iadecola C
. 2016.
Vascular and Metabolic Factors in Alzheimer's Disease and Related Dementias: Introduction.
.
Cell Mol Neurobiol. 36(2):151-4.
2017
Na ES
,
De Jesús-Cortés H
,
Martinez-Rivera A
,
Kabir ZD
,
Wang J
,
Ramesh V
,
Onder Y
,
Rajadhyaksha AM
,
Monteggia LM
,
Pieper AA
. 2017.
D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome.
.
PLoS One. 12(8):e0183026.
Fil D
,
DeLoach A
,
Yadav S
,
Alkam D
,
MacNicol M
,
Singh A
,
Compadre CM
,
Goellner JJ
,
O'Brien CA
,
Fahmi T
et al.
. 2017.
Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.
.
Hum Mol Genet. 26(4):686-701.
Marques-Lopes J
,
Tesfaye E
,
Israilov S
,
Van Kempen TA
,
Wang G
,
Glass MJ
,
Pickel VM
,
Iadecola C
,
Waters EM
,
Milner TA
. 2017.
Redistribution of NMDA Receptors in Estrogen-Receptor-β-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure.
.
Neuroendocrinology. 104(3):239-256.
Kabir ZD
,
Che A
,
Fischer DK
,
Rice RC
,
Rizzo BK
,
Byrne M
,
Glass MJ
,
Garcia NVDe Marco
,
Rajadhyaksha AM
. 2017.
Rescue of impaired sociability and anxiety-like behavior in adult cacna1c-deficient mice by pharmacologically targeting eIF2α.
.
Mol Psychiatry. 22(8):1096-1109.
2019
Moda-Sava RN
,
Murdock MH
,
Parekh PK
,
Fetcho RN
,
Huang BS
,
Huynh TN
,
Witztum J
,
Shaver DC
,
Rosenthal DL
,
Alway EJ
et al.
. 2019.
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.
.
Science. 364(6436)
2022
Burré J
,
Sharma M
. 2022.
Cellular And Small Animal Models Of Neurodegenerative Diseases.
.
J Vis Exp. (186)
Xia D
,
Lianoglou S
,
Sandmann T
,
Calvert M
,
Suh JH
,
Thomsen E
,
Dugas J
,
Pizzo ME
,
DeVos SL
,
Earr TK
et al.
. 2022.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
.
Mol Neurodegener. 17(1):41.
Yan Y
,
Wang X
,
Chaput D
,
Shin M-K
,
Koh Y
,
Gan L
,
Pieper AA
,
Woo J-AA
,
Kang DE
. 2022.
X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women.
.
Cell. 185(21):3913-3930.e19.
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