Publications

Lee C-T, Bendriem RM, Wu WW, Shen R-F.  2017.  3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders.. J Biomed Sci. 24(1):59.

Ranea-Robles P, Launay N, Ruiz M, Calingasan NYlagan, Dumont M, Naudí A, Portero-Otín M, Pamplona R, Ferrer I, M Beal F et al..  2018.  Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy.. EMBO Mol Med.

Brea D, Poon C, Murphy M, Lubitz G, Iadecola C, Anrather J.  2018.  Ablation of nasal-associated lymphoid tissue does not affect focal ischemic brain injury in mice.. PLoS One. 13(10):e0205470.

Intlekofer AM, Shih AH, Wang B, Nazir A, Rustenburg AS, Albanese SK, Patel M, Famulare C, Correa FM, Takemoto N et al..  2018.  Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations.. Nature.

Gaisina IN, Lee SH, Kaidery NA, Ben Aissa M, Ahuja M, Smirnova NN, Wakade S, Gaisin A, Bourassa MW, Ratan RR et al..  2018.  Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors.. ACS Chem Neurosci.

S Josephson A, Kamel H.  2018.  The Acute Stroke Care Revolution: Enhancing Access to Therapeutic Advances.. JAMA.

Kamel H.  2018.  Additional Factors in Considering Patent Foramen Ovale Closure to Prevent Recurrent Ischemic Stroke-Reply.. JAMA Neurol.

Ishii M, Iadecola C.  2016.  Adipocyte-derived factors in age-related dementia and their contribution to vascular and Alzheimer pathology.. Biochim Biophys Acta. 1862(5):966-74.

Morris NA, Merkler AE, Parker WE, Claassen J, E Connolly S, Sheth KN, Kamel H.  2016.  Adverse Outcomes After Initial Non-surgical Management of Subdural Hematoma: A Population-Based Study.. Neurocrit Care. 24(2):226-32.

Kobayashi M, Benakis C, Anderson C, Moore MJ, Poon C, Uekawa K, Dyke JP, Fak JJ, Mele A, Park CY et al..  2019.  AGO CLIP Reveals an Activated Network for Acute Regulation of Brain Glutamate Homeostasis in Ischemic Stroke.. Cell Rep. 28(4):979-991.e6.

Trubetckaia O, Lane AE, Qian L, Zhou P, Lane DA.  2019.  Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.. Commun Biol. 2:418.

Anderson CJ, Bredvik K, Burstein SR, Davis C, Meadows SM, Dash J, Case L, Milner TA, Kawamata H, Zuberi A et al..  2019.  ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response.. Acta Neuropathol.

Deng Z, Lim J, Wang Q, Purtell K, Wu S, Palomo GM, Tan H, Manfredi G, Zhao Y, Peng J et al..  2019.  ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.. Autophagy. :1-15.

Van Kempen TA, Narayan A, Waters EM, Marques-Lopes J, Iadecola C, Glass MJ, Pickel VM, Milner TA.  2016.  Alterations in the subcellular distribution of NADPH oxidase p47(phox) in hypothalamic paraventricular neurons following slow-pressor angiotensin II hypertension in female mice with accelerated ovarian failure.. J Comp Neurol. 524(11):2251-65.

Doczi J, Torocsik B, Echaniz-Laguna A, de Camaret BMousson, Starkov A, Starkova N, Gál A, Molnár MJ, Kawamata H, Manfredi G et al..  2016.  Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells.. Sci Rep. 6:26700.

Fischer DK, Rice RC, Rivera AMartinez, Donohoe M, Rajadhyaksha AM.  2017.  Altered reward sensitivity in female offspring of cocaine-exposed fathers.. Behav Brain Res. 332:23-31.

Garg A, Bansal M, Gotoh N, Feng G-S, Zhong J, Wang F, Kariminejad A, Brooks S, Zhang X.  2017.  Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis.. PLoS Genet. 13(10):e1007047.

Del Prete D, Rice RC, Rajadhyaksha AM, D'Adamio L.  2016.  Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.. J Biol Chem. 291(33):17209-27.

Ishii M, Hiller AJ, Pham L, McGuire MJ, Iadecola C, Wang G.  2019.  Amyloid-beta modulates low-threshold activated voltage-gated L-type calcium channels of arcuate neuropeptide Y neurons leading to calcium dysregulation and hypothalamic dysfunction.. J Neurosci.

Iadecola C.  2014.  Angiophagy: clearing or clogging microvessels? Sci Transl Med. 6(226):226fs10.

Shi Y, Yamada K, Liddelow SAntony, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC et al..  2017.  ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.. Nature. 549(7673):523-527.

Cao J, Gaamouch FEl, Meabon JS, Meeker KD, Zhu L, Zhong MB, Bendik J, Elder G, Jing P, Xia J et al..  2017.  ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.. Sci Rep. 7(1):11372.

Ishii M.  2019.  Apolipoprotein B as a New Link Between Cholesterol and Alzheimer Disease.. JAMA Neurol.

Koizumi K, Hattori Y, Ahn SJi, Buendia I, Ciacciarelli A, Uekawa K, Wang G, Hiller A, Zhao L, Voss HU et al..  2018.  Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function.. Nat Commun. 9(1):3816.

Navi BB, Reiner AS, Kamel H, Iadecola C, Okin PM, Tagawa ST, Panageas KS, DeAngelis LM.  2018.  Arterial thromboembolic events preceding the diagnosis of cancer in older persons.. Blood.