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Iadecola, Costantino
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Pearson CA
,
Iadecola C
. 2022.
When the BBB goes MIA.
.
Proc Natl Acad Sci U S A. 119(19):e2204159119.
Faraco G
,
Wijasa TStella
,
Park L
,
Moore J
,
Anrather J
,
Iadecola C
. 2014.
Water deprivation induces neurovascular and cognitive dysfunction through vasopressin-induced oxidative stress.
.
J Cereb Blood Flow Metab. 34(5):852-60.
V
Ruiz-Uribe NE
,
Bracko O
,
Swallow M
,
Omurzakov A
,
Dash S
,
Uchida H
,
Xiang D
,
Haft-Javaherian M
,
Falkenhain K
,
Lamont ME
et al.
. 2023.
Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimer’s disease.
.
bioRxiv.
Sweeney MD
,
Montagne A
,
Sagare AP
,
Nation DA
,
Schneider LS
,
Chui HC
,
Harrington MG
,
Pa J
,
Law M
,
Wang DJJ
et al.
. 2019.
Vascular dysfunction-The disregarded partner of Alzheimer's disease.
.
Alzheimers Dement. 15(1):158-167.
Iadecola C
,
Duering M
,
Hachinski V
,
Joutel A
,
Pendlebury ST
,
Schneider JA
,
Dichgans M
. 2019.
Vascular Cognitive Impairment and Dementia: JACC Scientific Expert Panel.
.
J Am Coll Cardiol. 73(25):3326-3344.
Iadecola C
. 2016.
Vascular and Metabolic Factors in Alzheimer's Disease and Related Dementias: Introduction.
.
Cell Mol Neurobiol. 36(2):151-4.
U
Hochrainer K
,
Pejanovic N
,
Olaseun VA
,
Zhang S
,
Iadecola C
,
Anrather J
. 2015.
The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation.
.
Nucleic Acids Res. 43(20):9889-904.
T
Ishii M
,
Wang G
,
Racchumi G
,
Dyke JP
,
Iadecola C
. 2014.
Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.
.
J Neurosci. 34(27):9096-106.
Uekawa K
,
Anfray A
,
Ahn SJi
,
Casey N
,
Seo J
,
Zhou P
,
Iadecola C
,
Park L
. 2024.
tPA supplementation preserves neurovascular and cognitive function in Tg2576 mice.
.
Alzheimers Dement. 20(7):4572-4582.
Park L
,
Zhou J
,
Koizumi K
,
Wang G
,
Anfray A
,
Ahn SJi
,
Seo J
,
Zhou P
,
Zhao L
,
Paul S
et al.
. 2020.
tPA Deficiency Underlies Neurovascular Coupling Dysfunction by Amyloid-β.
.
J Neurosci. 40(42):8160-8173.
Park L
,
Hochrainer K
,
Hattori Y
,
Ahn SJi
,
Anfray A
,
Wang G
,
Uekawa K
,
Seo J
,
Palfini V
,
Blanco I
et al.
. 2020.
Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration.
.
Nat Neurosci. 23(9):1079-1089.
Kamel H
,
Merkler AE
,
Iadecola C
,
Gupta A
,
Navi BB
. 2019.
Tailoring the Approach to Embolic Stroke of Undetermined Source: A Review.
.
JAMA Neurol.
S
Smith EE
,
Biessels GJan
,
Gao V
,
Gottesman RF
,
Liesz A
,
Parikh NS
,
Iadecola C
. 2024.
Systemic determinants of brain health in ageing.
.
Nat Rev Neurol.
Hochrainer K
,
Jackman K
,
Benakis C
,
Anrather J
,
Iadecola C
. 2015.
SUMO2/3 is associated with ubiquitinated protein aggregates in the mouse neocortex after middle cerebral artery occlusion.
.
J Cereb Blood Flow Metab. 35(1):1-5.
Kuceyeski A
,
Navi BB
,
Kamel H
,
Raj A
,
Relkin N
,
Toglia J
,
Iadecola C
,
O'Dell M
. 2016.
Structural connectome disruption at baseline predicts 6-months post-stroke outcome.
.
Hum Brain Mapp. 37(7):2587-601.
Brea D
,
Poon C
,
Benakis C
,
Lubitz G
,
Murphy M
,
Iadecola C
,
Anrather J
. 2021.
Stroke affects intestinal immune cell trafficking to the central nervous system.
.
Brain Behav Immun.
Iadecola C
,
Parikh NS
. 2019.
Statins and Cognitive Impairment: Not a Culprit, Protective in Some?
J Am Coll Cardiol. 74(21):2569-2571.
Hachinski V
,
Einhäupl K
,
Ganten D
,
Alladi S
,
Brayne C
,
Stephan BCM
,
Sweeney MD
,
Zlokovic B
,
Iturria-Medina Y
,
Iadecola C
et al.
. 2019.
Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto.
.
Int J Stroke. :1747493019871915.
Garcia-Bonilla L
,
Faraco G
,
Moore J
,
Murphy M
,
Racchumi G
,
Srinivasan J
,
Brea D
,
Iadecola C
,
Anrather J
. 2016.
Spatio-temporal profile, phenotypic diversity, and fate of recruited monocytes into the post-ischemic brain.
.
J Neuroinflammation. 13(1):285.
Yanagida K
,
Liu CH
,
Faraco G
,
Galvani S
,
Smith HK
,
Burg N
,
Anrather J
,
Sanchez T
,
Iadecola C
,
Hla T
. 2017.
Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1.
.
Proc Natl Acad Sci U S A. 114(17):4531-4536.
Merkler AE
,
Alakbarli J
,
Gialdini G
,
Navi BB
,
Murthy SB
,
Goyal P
,
Kim J
,
Devereux RB
,
Safford MM
,
Iadecola C
et al.
. 2019.
Short-Term Risk of Ischemic Stroke After Detection of Left Ventricular Thrombus on Cardiac Magnetic Resonance Imaging.
.
J Stroke Cerebrovasc Dis.
Eruysal E
,
Ravdin L
,
Zhang C
,
Kamel H
,
Iadecola C
,
Ishii M
. 2023.
Sexually Dimorphic Association of Circulating Plasminogen Activator Inhibitor-1 Levels and Body Mass Index with Cerebrospinal Fluid Biomarkers of Alzheimer's Pathology in Preclinical Alzheimer's Disease.
.
J Alzheimers Dis. 91(3):1073-1083.
Merkler AE
,
Gialdini G
,
Yaghi S
,
Okin PM
,
Iadecola C
,
Navi BB
,
Kamel H
. 2017.
Safety Outcomes After Percutaneous Transcatheter Closure of Patent Foramen Ovale.
.
Stroke. 48(11):3073-3077.
R
Merkler AE
,
Iadecola C
. 2017.
Rollercoaster Blood Pressure: An Alzheimer Disease Risk Factor?
Circulation. 136(6):526-528.
Garcia-Bonilla L
,
Sciortino R
,
Shahanoor Z
,
Racchumi G
,
Janakiraman M
,
Montaner J
,
Zhou P
,
Anrather J
,
Iadecola C
. 2021.
Role of microglial and endothelial CD36 in post-ischemic inflammasome activation and interleukin-1β-induced endothelial activation.
.
Brain Behav Immun.
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