Publications

Found 30 results
Author Title [ Type(Asc)] Year
Filters: Author is Manfredi, Giovanni  [Clear All Filters]
Journal Article
Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Hüttenhain R, Kauwe G et al..  2022.  Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.. Cell. 185(4):712-728.e14.
Fels JA, Manfredi G.  2019.  Sex Differences in Ischemia/Reperfusion Injury: The Role of Mitochondrial Permeability Transition.. Neurochem Res.
Fels JA, Casalena GA, Manfredi G.  2021.  Sex and oestrogen receptor β have modest effects on gene expression in the mouse brain posterior cortex.. Endocrinol Diabetes Metab. 4(1):e00191.
Chen Q, Kirk K, Shurubor YI, Zhao D, Arreguin AJ, Shahi I, Valsecchi F, Primiano G, Calder EL, Carelli V et al..  2018.  Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.. Cell Metab.
Jenkins ECharles, Casalena G, Gomez M, Zhao D, Kenny TC, Shah N, Manfredi G, Germain D.  2020.  Raloxifene is a female-specific proteostasis therapeutic in the spinal cord.. Endocrinology.
Kawamata H, Manfredi G.  2017.  Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.. J Cell Biol. 216(12):3917-3929.
Jenkins ECharles, Shah N, Gomez M, Casalena G, Zhao D, Kenny TC, Guariglia SRose, Manfredi G, Germain D.  2020.  Proteasome mapping reveals sexual dimorphism in tissue-specific sensitivity to protein aggregations.. EMBO Rep. :e48978.
Qu Y, Konrad C, Anderson C, Qian L, Yin T, Manfredi G, Iadecola C, Zhou P.  2020.  Prohibitin S-Nitrosylation Is Required for the Neuroprotective Effect of Nitric Oxide in Neuronal Cultures.. J Neurosci. 40(16):3142-3151.
Anderson CJ, Kahl A, Fruitman H, Qian L, Zhou P, Manfredi G, Iadecola C.  2019.  Prohibitin levels regulate OMA1 activity and turnover in neurons.. Cell Death Differ.
Anderson CJ, Kahl A, Qian L, Stepanova A, Starkov A, Manfredi G, Iadecola C, Zhou P.  2018.  Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress.. J Neurochem.
Palomo GM, Granatiero V, Kawamata H, Konrad C, Kim M, Arreguin AJ, Zhao D, Milner TA, Manfredi G.  2018.  Parkin is a disease modifier in the mutant SOD1 mouse model of ALS.. EMBO Mol Med.
Kuszak AJ, Espey MGraham, Falk MJ, Holmbeck MA, Manfredi G, Shadel GS, Vernon HJ, Zolkipli-Cunningham Z.  2017.  Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems.. Annu Rev Pathol.
Granatiero V, Konrad C, Bredvik K, Manfredi G, Kawamata H.  2019.  Nrf2 signaling links ER oxidative protein folding and calcium homeostasis in health and disease.. Life Sci Alliance. 2(5)
Kawamata H, Peixoto P, Konrad C, Palomo G, Bredvik K, Gerges M, Valsecchi F, Petrucelli L, Ravits JM, Starkov A et al..  2017.  Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.. Mol Neurodegener. 12(1):37.
Sayles NM, Southwell N, McAvoy K, Kim K, Pesini A, Anderson CJ, Quinzii C, Cloonan S, Kawamata H, Manfredi G.  2022.  Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.. Cell Rep. 38(10):110475.
Kenny TC, Manfredi G, Germain D.  2017.  The Mitochondrial Unfolded Protein Response as a Non-Oncogene Addiction to Support Adaptation to Stress during Transformation in Cancer and Beyond.. Front Oncol. 7:159.
Granatiero V, Manfredi G.  2019.  Mitochondrial Transport and Turnover in the Pathogenesis of Amyotrophic Lateral Sclerosis.. Biology (Basel). 8(2)
Manfredi G, Kawamata H.  2016.  Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.. Neurobiol Dis. 90:35-42.
Cornacchia D, Zhang C, Zimmer B, Chung SYoung, Fan Y, Soliman MA, Tchieu J, Chambers SM, Shah H, Paull D et al..  2019.  Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs.. Cell Stem Cell.
Fels JA, Casalena G, Konrad C, Holmes HE, Dellinger RW, Manfredi G.  2022.  Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301.. Hum Mol Genet.
Konrad C, Kawamata H, Bredvik KG, Arreguin AJ, Cajamarca SA, Hupf JC, Ravits JM, Miller TM, Maragakis NJ, Hales CM et al..  2017.  Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.. Mol Neurodegener. 12(1):76.
Burstein SR, Kim HJeong, Fels JA, Qian L, Zhang S, Zhou P, Starkov AA, Iadecola C, Manfredi G.  2018.  Estrogen receptor beta modulates permeability transition in brain mitochondria.. Biochim Biophys Acta.
Jenkins ECharles, O'Connell MJ, Manfredi G, Germain D.  2021.  Doxycycline promotes proteasome fitness in the central nervous system.. Sci Rep. 11(1):17003.
Hayes LR, Asress SA, Li Y, Galkin A, Stepanova A, Kawamata H, Manfredi G, Glass JD.  2019.  Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal.. Exp Neurol. 318:251-257.
Stepanova A, Shurubor Y, Valsecchi F, Manfredi G, Galkin A.  2016.  Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart.. Biochim Biophys Acta. 1857(9):1561-8.