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Found 40 results
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Manfredi, Giovanni
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Journal Article
Tracy TE
,
Madero-Pérez J
,
Swaney DL
,
Chang TS
,
Moritz M
,
Konrad C
,
Ward ME
,
Stevenson E
,
Hüttenhain R
,
Kauwe G
et al.
. 2022.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
.
Cell. 185(4):712-728.e14.
Sasset L
,
Chowdhury KH
,
Manzo OL
,
Rubinelli L
,
Konrad C
,
J Maschek A
,
Manfredi G
,
Holland WL
,
Di Lorenzo A
. 2023.
Sphingosine-1-phosphate controls endothelial sphingolipid homeostasis via ORMDL.
.
EMBO Rep. 24(1):e54689.
Colognesi M
,
Shkodra A
,
Gabbia D
,
Kawamata H
,
Manfredi PL
,
Manfredi G
,
De Martin S
. 2024.
Sex-dependent effects of the uncompetitive N-methyl-D-aspartate receptor antagonist REL-1017 in G93A-SOD1 amyotrophic lateral sclerosis mice.
.
Front Neurol. 15:1384829.
Fels JA
,
Manfredi G
. 2019.
Sex Differences in Ischemia/Reperfusion Injury: The Role of Mitochondrial Permeability Transition.
.
Neurochem Res.
Fels JA
,
Casalena GA
,
Manfredi G
. 2021.
Sex and oestrogen receptor β have modest effects on gene expression in the mouse brain posterior cortex.
.
Endocrinol Diabetes Metab. 4(1):e00191.
Chen Q
,
Kirk K
,
Shurubor YI
,
Zhao D
,
Arreguin AJ
,
Shahi I
,
Valsecchi F
,
Primiano G
,
Calder EL
,
Carelli V
et al.
. 2018.
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
.
Cell Metab.
Jenkins ECharles
,
Casalena G
,
Gomez M
,
Zhao D
,
Kenny TC
,
Shah N
,
Manfredi G
,
Germain D
. 2020.
Raloxifene is a female-specific proteostasis therapeutic in the spinal cord.
.
Endocrinology.
Kawamata H
,
Manfredi G
. 2017.
Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.
.
J Cell Biol. 216(12):3917-3929.
Jenkins ECharles
,
Shah N
,
Gomez M
,
Casalena G
,
Zhao D
,
Kenny TC
,
Guariglia SRose
,
Manfredi G
,
Germain D
. 2020.
Proteasome mapping reveals sexual dimorphism in tissue-specific sensitivity to protein aggregations.
.
EMBO Rep. :e48978.
Qu Y
,
Konrad C
,
Anderson C
,
Qian L
,
Yin T
,
Manfredi G
,
Iadecola C
,
Zhou P
. 2020.
Prohibitin S-Nitrosylation Is Required for the Neuroprotective Effect of Nitric Oxide in Neuronal Cultures.
.
J Neurosci. 40(16):3142-3151.
Anderson CJ
,
Kahl A
,
Fruitman H
,
Qian L
,
Zhou P
,
Manfredi G
,
Iadecola C
. 2019.
Prohibitin levels regulate OMA1 activity and turnover in neurons.
.
Cell Death Differ.
Anderson CJ
,
Kahl A
,
Qian L
,
Stepanova A
,
Starkov A
,
Manfredi G
,
Iadecola C
,
Zhou P
. 2018.
Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress.
.
J Neurochem.
Palomo GM
,
Granatiero V
,
Kawamata H
,
Konrad C
,
Kim M
,
Arreguin AJ
,
Zhao D
,
Milner TA
,
Manfredi G
. 2018.
Parkin is a disease modifier in the mutant SOD1 mouse model of ALS.
.
EMBO Mol Med.
Kuszak AJ
,
Espey MGraham
,
Falk MJ
,
Holmbeck MA
,
Manfredi G
,
Shadel GS
,
Vernon HJ
,
Zolkipli-Cunningham Z
. 2017.
Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems.
.
Annu Rev Pathol.
Granatiero V
,
Konrad C
,
Bredvik K
,
Manfredi G
,
Kawamata H
. 2019.
Nrf2 signaling links ER oxidative protein folding and calcium homeostasis in health and disease.
.
Life Sci Alliance. 2(5)
Kawamata H
,
Peixoto P
,
Konrad C
,
Palomo G
,
Bredvik K
,
Gerges M
,
Valsecchi F
,
Petrucelli L
,
Ravits JM
,
Starkov A
et al.
. 2017.
Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.
.
Mol Neurodegener. 12(1):37.
Sayles NM
,
Southwell N
,
McAvoy K
,
Kim K
,
Pesini A
,
Anderson CJ
,
Quinzii C
,
Cloonan S
,
Kawamata H
,
Manfredi G
. 2022.
Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.
.
Cell Rep. 38(10):110475.
Kenny TC
,
Manfredi G
,
Germain D
. 2017.
The Mitochondrial Unfolded Protein Response as a Non-Oncogene Addiction to Support Adaptation to Stress during Transformation in Cancer and Beyond.
.
Front Oncol. 7:159.
Granatiero V
,
Manfredi G
. 2019.
Mitochondrial Transport and Turnover in the Pathogenesis of Amyotrophic Lateral Sclerosis.
.
Biology (Basel). 8(2)
Manfredi G
,
Kawamata H
. 2016.
Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.
.
Neurobiol Dis. 90:35-42.
Woo E
,
Bredvik K
,
Liu B
,
Fuchs TJ
,
Manfredi G
,
Konrad C
. 2023.
Machine learning approaches based on fibroblast morphometry do not predict ALS.
.
Neurobiol Aging. 130:80-83.
Cornacchia D
,
Zhang C
,
Zimmer B
,
Chung SYoung
,
Fan Y
,
Soliman MA
,
Tchieu J
,
Chambers SM
,
Shah H
,
Paull D
et al.
. 2019.
Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs.
.
Cell Stem Cell.
Yang S
,
Le Kernec J
,
Romain O
,
Fioranelli F
,
Cadart P
,
Fix J
,
Ren C
,
Manfredi G
,
Letertre T
,
Saenz IDavid Hino
et al.
. 2023.
The Human Activity Radar Challenge: benchmarking based on the 'Radar signatures of human activities' dataset from Glasgow University.
.
IEEE J Biomed Health Inform. PP
Southwell N
,
Zhao D
,
Sayles NM
,
Dash J
,
Fujita K
,
Aurelio MDâ
,
Manfredi G
,
Kawamata H
. 2023.
High fat diet ameliorates the mitochondrial cardiomyopathy of CHCHD10 mutant mice.
.
bioRxiv.
Southwell N
,
Manzo O
,
Bacman S
,
Zhao D
,
Sayles NM
,
Dash J
,
Fujita K
,
D'Aurelio M
,
Di Lorenzo A
,
Manfredi G
et al.
. 2024.
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
.
EMBO Mol Med.
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